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ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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Kidney Week

Basic/Clinical Science Session

Not to Be Overlooked: Novel Discoveries in Proximal Tubular Transport and Physiology

October 22, 2020 | 10:00 AM - 12:00 PM

Location: On-Demand

Session Description

The proximal tubule is responsible for approximately 70% of the exchange by tubular epithelial cells, but compared with the distal nephron, little is known about how proximal tubular functions of reabsorption, secretion, and synthesis are regulated. Recent studies have uncovered novel aspects of proximal tubule function. This session explores novel insights into proximal tubular transport and physiology with implications for health and disease.

ASN welcomes the ASN/ERA-EDTA Young Nephrologist Exchange Speaker at Kidney Week, Lisa Gianesello, MS, PhD. ASN and ERA-EDTA are committed to supporting young and aspiring nephrologists at both organizations and created this annual speaker exchange to highlight outstanding, early-career nephrologists to present at ASN Kidney Week and the ERA-EDTA Congress.

Learning Objective(s)

  • Examine the determinants of oxalate transport and potential risks for nephrolithiasis
  • Elucidate the molecular regulators of Na-Pi2 and evaluate its role as a therapeutic target
  • Describe the role of insulin signaling in the proximal tubule
  • Describe the role of chloride channels in protein reabsorption

Learning Pathway(s)

  • Cell and Transport Physiology
  • Bone and Mineral Metabolism


  • David B. Mount, MD
  • Brandi M. Wynne, MS, PhD


  • Molecular Determinants of Oxalate Transport
    10:00 AM - 10:30 AM
    Peter S. Aronson, MD, FASN
  • Mechanisms of Na-Pi2 Regulation
    10:30 AM - 11:00 AM
    Timo Rieg, MD, PhD 
  • Insulin and the Proximal Tubule
    11:00 AM - 11:30 AM
    Carolyn M. Ecelbarger, PhD 
  • Dent Disease and Protein Reabsorption
    11:30 AM - 12:00 PM
    Lisa Gianesello, MS, PhD