Kidney Architecture: Building Blocks and Organization
October 24, 2020 | 10:30 AM - 12:30 PM
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Basic/Clinical Science Session
Kidney Architecture: Building Blocks and Organization
October 24, 2020 | 10:30 AM - 12:30 PM
Location: Simulive
Session Description
This session focuses on how the kidney assumes its form, which is essential for its physiological function.
Learning Objective(s)
- Define the principles underlying radial growth of the human kidney
- Describe the cellular and molecular mechanisms controlling kidney organogenesis
Learning Pathway(s)
- Development and Pediatrics
- Genetic Diseases of the Kidneys
Moderators
- Jordan A. Kreidberg, MD, PhD
- Lori L. O'Brien, PhD
Presentations
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Morphogenetic Drivers of Kidney Architecture
10:30 AM - 11:00 AM
Ian Smyth, PhD
Ian Smyth, PhD
Professor Ian Smyth is an NH&MRC Senior Research Fellow at Monash University in Melbourne, Australia. He co-heads the Development and Stem Cells Program at the Monash Biomedicine Institute and is the Deputy Head (Research) of the Department of Anatomy and Developmental Biology. His doctoral studies at the University of Queensland focused on understanding the role of the PATCHED genes in human disease. He then undertook postdoctoral work in Edinburgh, Houston and London using forward genetic screens in mice to identify novel genes involved in skin and kidney development and disease. His group’s work focuses on two specific questions: how development of the fetal renal collecting duct system is impacted by genetic mutation and environmental perturbation and how disruption of signaling in these cells in the adult kidney gives rise to cysts in ciliopathy patients.
Morphogenetic Drivers of Kidney Architecture
October 24, 2020 | 10:30 AM - 11:00 AM
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Cell Types and Patterning Functions of the Kidney Interstitium
11:00 AM - 11:30 AM
Thomas J. Carroll, PhD
Cell Types and Patterning Functions of the Kidney Interstitium
October 24, 2020 | 11:00 AM - 11:30 AM
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Formation of the Kidney Lymphatic System
11:30 AM - 12:00 PM
David A. Long, PhD
Formation of the Kidney Lymphatic System
October 24, 2020 | 11:30 AM - 12:00 PM
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Structural Malformations: Mouse Models of Vesicoureteral Reflux
12:00 PM - 12:30 PM
Indra R. Gupta, MD
Indra R. Gupta, MD
Dr. Indra R. Gupta is a clinician-scientist and pediatric nephrologist. She is Professor in the Department of Pediatrics at McGill University and an Associate Member in the Departments of Human Genetics and Experimental Medicine. Her laboratory is focused on understanding the molecular and cellular mechanisms that result in congenital anomalies of the kidneys and urinary tract with a special interest in vesico-ureteric reflux. She is currently Interim Director of Child Health Research at the Research Institute of the McGill University Health Centre.
Structural Malformations: Mouse Models of Vesicoureteral Reflux
October 24, 2020 | 12:00 PM - 12:30 PM
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