Kidney Week

Basic/Clinical Science Session

Mediators and Protectors in AKI

October 25, 2020 | 10:30 AM - 12:30 PM

Location: Simulive

Session Description

AKI results from an interplay among the epithelial cell, the endothelial cell, other vascular cells, and inflammatory processes, along with abnormalities in renal energetics. This session presents newly discovered mechanisms and participants in AKI as well as pathways that mediate protection and promote recovery from AKI.

Learning Objective(s)

• Discuss newly discovered mechanisms of AKI
• Describe the protective pathways in AKI

Learning Pathway(s)

• Acute Kidney Injury

Moderators

• Subhashini Bolisetty, PhD
• Lisa Robinson, MD, FASN

Presentations

• Protein Translation in Septic AKI
  10:30 AM - 11:00 AM
  Pierre C. Dagher, MD, FASN 
  
  

  Pierre C. Dagher, MD, FASN

Protein Translation in Septic AKI

October 25, 2020 | 10:30 AM - 11:00 AM

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• Remote Organ Effects of AKI on Cardiac and Pulmonary Function
  11:00 AM - 11:30 AM
  Sarah Faubel, MD
  

  Sarah Faubel, MD

Remote Organ Effects of AKI on Cardiac and Pulmonary Function

October 25, 2020 | 11:00 AM - 11:30 AM

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• Prolyl Hydroxylase Inhibition in Protection from AKI
  11:30 AM - 12:00 PM
  Marie Ito, MD, PhD 
  
  

  Marie Ito, MD, PhD

  Marie Ito is medical doctor of the hemodialysis and apheresis department in the university of Tokyo Hospital and postdoctoral researcher. She was received the Ph. D. degree in Medicine from the university of Tokyo, Japan, in 2019. Her research interest includes acute kidney injury, chronic kidney disease and hypoxia.

Prolyl Hydroxylase Inhibition in Protection from AKI

October 25, 2020 | 11:30 AM - 12:00 PM

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• Metabolism and the Kidney in AKI
  12:00 PM - 12:30 PM
  Sarah C. Huen, MD, PhD 
  
  

  Sarah C. Huen, MD, PhD

  Sarah Huen, M.D., Ph.D., is an Assistant Professor at the University of Texas Southwestern Medical Center in the Departments of Internal Medicine (Nephrology) and Pharmacology. Dr. Huen received her medical degree from Northwestern University. She completed Internal Medicine residency training at New York University Medical Center and Nephrology fellowship training at Yale University. She then completed a Ph.D. program in Investigative Medicine at Yale in the laboratory of Dr. Lloyd Cantley studying the role of macrophages in ischemic kidney injury. As a post-doctoral fellow in the laboratory of Dr. Ruslan Medzhitov at Yale, Dr. Huen investigated the metabolic requirements of tissue tolerance in bacterial and viral inflammation. Dr. Huen joined the faculty at UT Southwestern in 2017. Dr. Huen’s research interests include investigating renal metabolism in sepsis. Her laboratory is also exploring metabolic defense pathways that promote organismal tissue protection and survival in the context of infection-related inflammation.

Metabolism and the Kidney in AKI

October 25, 2020 | 12:00 PM - 12:30 PM

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