Basic/Clinical Science Session
New Kids on the Block: AKI-to-CKD Progression
October 22, 2020 | 02:30 PM - 04:30 PM
Location: Live-Streamed
Session Description
AKI and CKD are known to mutually reinforce each other, resulting in poor outcomes in patients. Recent publications have elucidated mechanisms of maladaptive repair from AKI, particularly cell cycle arrest and the primary role of proximal tubule in initiating tubulointerstitial fibrosis. Novel methodologies have been used to explore the molecular underpinnings of this integrated syndrome. This session discusses emerging literature on the mechanisms of recovery, repair, and transition to CKD after AKI.
Learning Objective(s)
- Describe the molecular mechanisms in transition of AKI to CKD
- Explain the process of repair and recovery from AKI
Learning Pathway(s)
- Acute Kidney Injury
- Chronic Kidney Disease
Moderators
- Leslie S. Gewin, MD
- Danielle Soranno, MD
Presentations
- Role of FOXM1 in Repair from AKI
02:30 PM - 03:00 PM
Monica Chang Panesso, MD
- Role of Proximal Tubule in Maladaptive Recovery from AKI
03:00 PM - 03:30 PM
Craig R. Brooks, PhD
- FOXO3 Activation in AKI to CKD Transition
03:30 PM - 04:00 PM
Fangming Lin, MD, PhD, FASN
- Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR) in AKI and CKD
04:00 PM - 04:30 PM
Jochen Reiser, MD, PhD