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ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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Kidney Week

Basic/Clinical Science Session

New Kids on the Block: AKI-to-CKD Progression

October 22, 2020 | 02:30 PM - 04:30 PM

Location: Live-Streamed

Session Description

AKI and CKD are known to mutually reinforce each other, resulting in poor outcomes in patients. Recent publications have elucidated mechanisms of maladaptive repair from AKI, particularly cell cycle arrest and the primary role of proximal tubule in initiating tubulointerstitial fibrosis. Novel methodologies have been used to explore the molecular underpinnings of this integrated syndrome. This session discusses emerging literature on the mechanisms of recovery, repair, and transition to CKD after AKI.

Learning Objective(s)

  • Describe the molecular mechanisms in transition of AKI to CKD
  • Explain the process of repair and recovery from AKI

Learning Pathway(s)

  • Acute Kidney Injury
  • Chronic Kidney Disease


  • Leslie S. Gewin, MD
  • Danielle Soranno, MD


  • Role of FOXM1 in Repair from AKI
    02:30 PM - 03:00 PM
    Monica Chang Panesso, MD
  • Role of Proximal Tubule in Maladaptive Recovery from AKI
    03:00 PM - 03:30 PM
    Craig R. Brooks, PhD
  • FOXO3 Activation in AKI to CKD Transition
    03:30 PM - 04:00 PM
    Fangming Lin, MD, PhD, FASN
  • Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR) in AKI and CKD
    04:00 PM - 04:30 PM
    Jochen Reiser, MD, PhD