Disease Mechanisms and Treatment Concepts in IgA Nephropathy
October 22, 2020 | 02:30 PM - 04:30 PM
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Clinical Practice Session
Disease Mechanisms and Treatment Concepts in IgA Nephropathy
October 22, 2020 | 02:30 PM - 04:30 PM
Location: Simulive
Session Description
IgA nephropathy is the most common glomerulonephritis worldwide. This session reviews recent advances in our understanding of genetic factors and the contribution of aberrant IgA1 O-linked glycosylation to IgA nephropathy. Treatment approaches ranging from supportive measures to steroids and immunosuppressive drugs are discussed based on a case vignette and updated KDIGO guidelines. Clinical and histological disease features that may assist in predicting patient outcome are also analyzed.
Support is provided by an educational grant from Chinook Therapeutics, Inc.
Learning Objective(s)
- Describe recent advances in understanding the pathogenesis of IgA nephropathy
- Highlight the pros and cons of supportive versus immune-modulating treatments in IgA nephropathy
- Discuss the rationale for the updated KDIGO guidelines
- Identify and evaluate risk prediction tools in the clinical management of patients with IgA nephropathy
Learning Pathway(s)
- Glomerular Diseases
- Pathology
Moderators
- Brad H. Rovin, MD, FASN
- Shikha Wadhwani, MD, MS
Presentations
- Recent Advances in the Pathogenesis of IgA Nephropathy
02:30 PM - 03:00 PM
Pietro A. Canetta, MD, MS
Pietro A. Canetta, MD, MS
Recent Advances in the Pathogenesis of IgA Nephropathy
October 22, 2020 | 02:30 PM - 03:00 PM
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- At Least Steroids Are in Order for This IgA Nephropathy Patient
03:00 PM - 03:30 PM
Heather N. Reich, MD, PhD
Heather N. Reich, MD, PhD
At Least Steroids Are in Order for This IgA Nephropathy Patient
October 22, 2020 | 03:00 PM - 03:30 PM
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- Supportive Measures Will Do for This IgA Nephropathy Patient
03:30 PM - 04:00 PM
Jürgen Floege, MD
Supportive Measures Will Do for This IgA Nephropathy Patient
October 22, 2020 | 03:30 PM - 04:00 PM
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- One and One Is Three: Predicting Patient Outcome in IgA Nephropathy
04:00 PM - 04:30 PM
Sean Barbour, MD
Sean Barbour, MD
I completed my internal medicine and nephrology training at the University of British Columbia (BC) in 2010. I subsequently did a three-year glomerulonephritis fellowship and Master of Science in clinical epidemiology at the University of Toronto. I am an Associate Professor with the UBC Division of Nephrology, with a clinical and research focus on glomerular diseases. I am the Medical Lead and Chair of the BC Renal Glomerulonephritis Committee and GN Registry. Through these positions, I am responsible for health policy and health services related to glomerular diseases in BC. My research focus is on clinical trials, health outcomes and health services delivery in glomerulonephritis, and using prediction modeling techniques to improve risk stratification in glomerular diseases. I hold multiple peer-reviewed grants, including from the Michael Smith Foundation for Health Research, the Kidney Foundation of Canada, and the Canadian Institutes of Health Research.
One and One Is Three: Predicting Patient Outcome in IgA Nephropathy
October 22, 2020 | 04:00 PM - 04:30 PM
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