New Era of Anemia of CKD After the Nobel Prize
October 23, 2020 | 01:00 PM - 02:00 PM
Click an icon below to load this item into your calendar. Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Educational Symposium
New Era of Anemia of CKD After the Nobel Prize
October 23, 2020 | 01:00 PM - 02:00 PM
Location: Simulive
Session Description
Researchers who discovered how cells sense and adapt to changing oxygen availability were awarded the Nobel Prize in Physiology or Medicine in 2019. Hypoxia-inducible factor (HIF) is a master regulator of adaptive responses to hypoxia and controls the expression of erythropoietin. HIF-prolyl hydroxylase inhibitors stabilize the HIF complex and stimulate endogenous erythropoietin production, even in patients with kidney failure, and may have a role in suppressing the progression of CKD as well as renal anemia.
This symposium covers the basic mechanisms of oxygen sensing and novel therapeutic approaches of anemia in CKD using the oxygen-sensing system.
Support is provided by an educational grant from AstraZeneca Pharmaceuticals LP in collaboration with FibroGen.
Learning Objective(s)
- Describe oxygen-sensing mechanisms
- Discuss appropriate use of HIF-prolyl hydroxylase inhibitors
Learning Pathway(s)
Moderator
Presentations
- Introduction
01:00 PM - 01:10 PM
Jodie L. Babitt, MD
Introduction
October 23, 2020 | 01:00 PM - 01:10 PM
Click an icon below to load this item into your calendar. Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
- Oxygen Biology and the Nobel Prize
01:10 PM - 01:35 PM
Volker H. Haase, MD, DrMed
Volker H. Haase, MD, DrMed
Professor Volker Hans Haase is a physician-scientist with clinical training in Internal Medicine and Nephrology. Professor Haase holds the Krick-Brooks Chair in Nephrology at Vanderbilt University School of Medicine, where he serves as a Professor of Medicine and Professor of Molecular Physiology and Biophysics. His research interests are in oxygen and mitochondrial metabolism, HIF biology, renal anemia and molecular mechanisms of acute and chronic kidney injury. More information about Professor Haase's research group and clinical activities can be found at www.haaselab.org.
Oxygen Biology and the Nobel Prize
October 23, 2020 | 01:10 PM - 01:35 PM
Click an icon below to load this item into your calendar. Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
- New Era of Anemia Treatment
01:35 PM - 02:00 PM
Masaomi Nangaku, MD, PhD
New Era of Anemia Treatment
October 23, 2020 | 01:35 PM - 02:00 PM
Click an icon below to load this item into your calendar. Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
