ASN's Mission

ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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1401 H St, NW, Ste 900, Washington, DC 20005


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Kidney Week

Clinical Practice Session

Who, What, and Where for Newer Drugs for Diabetic Kidney Disease: Joint ASN-ADA Session

November 07, 2021 | 10:00 AM - 12:00 PM

Location: Live-Stream, Virtual Only

Session Description

Sodium-glucose cotransporter 2 (SGLT2) inhibitors, glucagon-like peptide 1 (GLP1) agonists, and mineralocorticoid receptor antagonists (MRAs) reduce GFR loss in diabetic kidney disease (DKD). This session discusses the underlying mechanisms that need to be better understood when determining their use.

ASN thanks the American Diabetes Association for assistance with this session.

Learning Objective(s)

  • Discuss how SGLT2 inhibitors act on the kidney in the short-term and in the long-term
  • Describe the evidence for the acute effects of GLP1 agonists on the kidney and why they reduce proteinuria and progressive loss of GFR
  • Identify the differences between steroidal and nonsteroidal MRA effects on potassium handling and kidney function decline
  • Outline which drugs are essential for current treatment of patients with DKD

Learning Pathway(s)

  • Diabetes and Metabolism
  • Chronic Kidney Disease


  • Radica Z. Alicic, MD, MS
  • Johannes F. Mann, MD, DrMed


  • Mechanisms of Kidney Protection of SGLT2 Inhibitors
    10:00 AM - 10:30 AM
    Volker Vallon, MD, FASN
  • Mechanisms of Kidney Protection of GLP1 Receptor Agonists
    10:30 AM - 11:00 AM
    Jens Juul Holst, DrMed, MD
  • Mechanisms of Kidney Protection of Steroidal and Nonsteroidal Mineralocorticoid Receptor Antagonists
    11:00 AM - 11:30 AM
    Rajiv Agarwal, MD, MBBS, MS, FASN
  • Essential Drugs in Patients with Diabetic Kidney Disease
    11:30 AM - 12:00 PM
    Katherine R. Tuttle, MD, FASN