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ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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Kidney Week

Basic/Clinical Science Session

The Pressure Is On: Update on Mechanisms of Salt-Sensitive Hypertension

November 05, 2021 | 10:00 AM - 12:00 PM

Location: On-Demand, Virtual Only

Session Description

Salt-sensitive hypertension is an important contributor to excessive cardiovascular morbidity and mortality. This session explores the processes involved in the development of salt sensitivity. Particular emphasis is given to genetic, oxidant, immune, and renal mechanisms of this hypertension phenotype.

Learning Objective(s)

  • Discuss the potential role of clock genes in the development of salt sensitivity
  • Describe several mechanisms of salt sensitivity
  • Describe how salt-induced hydrogen peroxide production negatively regulates renal sodium transport
  • Explain how chromosome 1 of the Brown Norway rat can influence salt sensitivity in the Dahl SS rat

Learning Pathway(s)

  • Hypertension and CVD


  • Abhijit V. Kshirsagar, MD, FASN, MPH
  • Clintoria R. Williams, PhD


  • Renal Hydrogen Peroxide Production Prevents Salt-Sensitive Hypertension
    10:00 AM - 12:00 PM
    Pedro A. Jose, MD, PhD
  • SS.BN1 Modulates Renal Vascular Function and Salt Sensitivity
    10:00 AM - 12:00 PM
    Aaron J. Polichnowski, PhD
  • Collecting Duct Bmal1 Regulates BP in a Sex-Dependent Manner
    10:00 AM - 12:00 PM
    David M. Pollock, PhD, FASN
  • Immune Modulation of Hypertension
    10:00 AM - 12:00 PM
    Annet Kirabo, MS, PhD, DVM