ASN's Mission

ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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Kidney Week

Basic/Clinical Science Session

Determinants of Renal Transport: Beyond the Usual Suspects

November 06, 2021 | 10:30 AM - 12:30 PM

Location: Live-Stream, Virtual Only

Session Description

Transcellular transport processes in the kidney depend on specific transport proteins, which are regulated by changes in gene expression, protein phosphorylation, and membrane trafficking. In this session, expert presenters highlight determinants of renal transport that go beyond, exploring, for example, the implications of cell metabolism for tubular transport. Why is tubular flow sensing important for transport regulation? What is the relevance and regulation of paracellular transport? Mathematical modeling is used to shed new light on sex as a determinant of renal transport.

Learning Objective(s)

  • Define how cell metabolism determines tubular transport
  • Describe how kidney epithelia sense tubular flow to regulate renal electrolyte transport
  • Discuss the relevance and regulation of paracellular transport in the kidney
  • Explain how mathematical modeling helps us understand sex differences in renal epithelial transport

Learning Pathway(s)

  • Cell and Transport Physiology
  • Hypertension and CVD


  • Robert S. Hoover, MD, FASN
  • Aylin R. Rodan, MD, PhD, FASN