ASN's Mission

ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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Kidney Week

Translational Session

One Cell at a Time: Application of Single-Cell RNA Sequencing in Kidney Transplantation

November 04, 2021 | 10:30 AM - 12:30 PM

Location: Live-Stream, Virtual Only

Session Description

Single-cell RNA sequencing is an exciting new approach to unraveling cell types and cell states at a hitherto unavailable molecular level of precision. This session reviews the application of this technology in kidney transplantation.

Learning Objective(s)

  • Describe single-cell RNA sequencing and summarize the application of this technology to studying kidney allografts
  • Discuss the critical importance of quality control and data analyses when applying single-cell approaches
  • Describe the advantages of single-nucleus RNA sequencing when using small archival samples
  • Explain the relevance of discerning cell-cell interactions and identification of cell states and rare cell populations in the kidney graft
  • Summarize some of the biological insights gained from multimodal studies in kidney transplantation and discuss the challenges and opportunities in this emerging field

Learning Pathway(s)

  • Transplantation/Immunology
  • Genetic Diseases of the Kidneys


  • Jonathan S. Maltzman, MD, PhD, FASN
  • Haojia Wu, PhD