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ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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Kidney Week

Educational Symposium

Update on Genetic Architecture and Therapy of Polycystic Kidney Diseases

November 04, 2021 | 12:45 PM - 01:45 PM

Location: Simulive, Virtual Only

Session Description

Monogenic polycystic kidney diseases (PKD) are the most common genetic cause of ESKD worldwide. PKD may follow an autosomal or recessive inheritance pattern. Most cases are due to mutations in one of three genes: PKD1 encoding for polycystin 1, PKD2 encoding for polycystin 2, or PKHD1 encoding for fibrocystin/polyductin (the recessive inheritance). However, recent advances in genomics and bioinformatics have led to the identification of other genetic causes of monogenic PKD, better understanding of the genetic architecture, and new therapeutic targets.

This symposium provides updates on the genetics of PKD and therapeutics for their treatment.

Support is provided by an educational grant from Otsuka America Pharmaceutical, Inc.

Learning Objective(s)

  • Describe the genetics of PKD
  • Discuss current approaches to treating PKD

Learning Pathway(s)

  • Genetic Diseases of the Kidneys

Moderator

  • Rasheed A. Gbadegesin, MD, MBBS, FASN

Presentations

  • Introduction
    12:45 PM - 12:55 PM
    Rasheed A. Gbadegesin, MD, MBBS, FASN
  • Genetic Architecture of PKD
    12:55 PM - 01:20 PM
    Lisa M. Guay-Woodford, MD
  • Recent Advances in the Treatment of PKD
    01:20 PM - 01:45 PM
    Vicente E. Torres, MD, PhD