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To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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Kidney Week

Educational Symposium

Hyperphosphatemia Management in Adults Treated with Dialysis for Kidney Failure: Old Lessons, New Directions

November 04, 2022 | 12:45 PM - 01:45 PM

Location: Regency Ballroom S, Hyatt Regency Orlando

Session Description

Hyperphosphatemia is a primary hallmark of CKD, particularly in people with ESKD. Most people with ESKD who are on dialysis are hyperphosphatemic; almost all people with dialysis-dependent kidney failure experience hyperphosphatemia at some point during the course of their disease. As a complex condition, treatment often requires a multilevel approach delivered by a multidisciplinary team.

This symposium reviews the fundamentals of phosphorus metabolism in conjunction with advancements in the understanding of cellular transports and biology and the development of novel pharmacologic or other treatments for hyperphosphatemia. Also discussed are nutritional and lifestyle approaches to optimizing health outcomes. This symposium further considers emerging evidence from clinical trials for weighing the efficacy of a treatment against the complexity of implementing and maintaining the treatment plan.

Support is provided by an educational grant from Akebia Therapeutics, Inc.

Learning Objective(s)

  • Describe the current burden, severity, and associated health conditions of hyperphosphatemia in diverse adult patient populations receiving dialysis for kidney failure
  • Describe the pathophysiology of hyperphosphatemia in kidney disease and how it informs current and emerging pharmacologic approaches
  • Discuss the effect of diet on hyperphosphatemia and the related opportunity to improve outcomes

Learning Pathway(s)

  • Fluid‚ Electrolyte‚ and Acid-Base Disorders
  • Bones‚ Stones‚ and Mineral Metabolism


  • Ebele M. Umeukeje, MD, FASN, MPH


  • Introduction
    12:45 PM - 12:55 PM
    Ebele M. Umeukeje, MD, FASN, MPH
  • Phosphorus Metabolism in Kidney Failure: How Biology Informs Medication Therapy
    12:55 PM - 01:15 PM
    Sagar U. Nigwekar, MD
  • Diet Strategies to Improve Hyperphosphatemia Independent of and Integrated with Medication Therapy
    01:15 PM - 01:35 PM
    Kathleen M. Hill Gallant, PhD, RD
  • Questions and Answers
    01:35 PM - 01:45 PM