ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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Kidney Week

Basic/Clinical Science Session

Organoids with PKD: Defining What They Are and What They Can Do for Us

November 02, 2023 | 02:00 PM - 04:00 PM

Location: Room 105, Pennsylvania Convention Center

Session Description

In this session, participants hear from researchers who have designed organoid systems that are affected by PKD genotypes. Participants hear about different approaches using human cells from urine, adult kidneys, or pluripotent stem cells, with help of bioengineering, and learn what human kidney organoids or tubuloids have taught us about the biology of in vitro cell culture, cysts, treatments, and identification of cell types capable of forming these structures.

Learning Objective(s)

  • Discuss advances and limitations of modeling kidneys in 3D culture
  • Evaluate how bioengineering approaches can contribute to improving kidney organoids and the conclusions we can draw from them
  • Specify an approach to multiplex organoids to test therapies
  • Describe the cellular basis of kidney tubuloids derived from adult human cells

Learning Pathway(s)

  • Genetic Diseases and Development
  • Kidney Biology and Physiology