ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

learn more

Contact ASN

1401 H St, NW, Ste 900, Washington, DC 20005


The Latest on X

Kidney Week

Basic/Clinical Science Session

Chloride Channels: Physiologic and Pathophysiologic Relevance

November 02, 2023 | 10:30 AM - 12:30 PM

Location: Room 114 (Nutter Theatre), Pennsylvania Convention Center

Session Description

Chloride channels play an important role of electrolyte homeostasis. Mutations of chloride channels cause renal salt wasting and cyst formation. This session focuses on the physiologic and pathophysiologic relevance of chloride channels and new findings of CIC channels underlying disease processes. The session also discusses the potential drug candidates on CIC channel/transporters and their clinical implications.

Learning Objective(s)

  • Discuss the physiologic and pathophysiologic roles of CIC channels
  • Explain the novel role of CIC5 in renal cyst development
  • Describe the novel role of CICK2 in renal medulla development and salt wasting
  • Outline the potential drug candidates for chloride channels/transporters

Learning Pathway(s)

  • Fluid‚ Electrolyte‚ and Acid-Base Disorders
  • Kidney Biology and Physiology