Basic/Clinical Science Session
Novel Roles of Channels and Transporters in Kidney Diseases and CVD
November 04, 2023 | 02:00 PM - 04:00 PM
Location: Room 111, Pennsylvania Convention Center
Session Description
Channels and/or transporters in the kidneys and the cardiovascular systems play a significant role in maintaining BP and electrolyte balance. Functional alterations of channels and/or transporters will lead to different disease phenotypes. This session focuses on the novel modulators of channels and/or transporters and their associated disease phenotypes in the kidneys and cardiovascular systems.
Learning Objective(s)
- Describe the novel role of histamine receptors in ENaC regulation
- Explain the new target of SGLT2 inhibitors in the heart
- Examine the novel role of the Piezo1 channel in kidney fibrosis
- Discuss the novel urea transporter role in cardiomyopathy in CKD
Learning Pathway(s)
- Fluid‚ Electrolyte‚ and Acid-Base Disorders
- Hypertension and Cardiorenal Disorders
Moderators
Presentations
- Novel Role of Histamine Receptors in the Regulation of Renal Epithelial Sodium Channel (ENaC)
02:00 PM - 02:30 PM
- Targeting the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Calcium: A New Therapeutic Approach to PKD
02:30 PM - 03:00 PM
- Mechanosensitive Piezo1 Channels Mediate Kidney Fibrosis
03:00 PM - 03:30 PM
- Inhibition of Urea Transporter Ameliorates Uremic Cardiomyopathy in CKD
03:30 PM - 04:00 PM