ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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Kidney Week

Translational Session

Advances in the Use of Immunofluorescence and Immunohistochemistry in Kidney Biopsy Evaluation

November 04, 2023 | 02:00 PM - 04:00 PM

Location: Room 113, Pennsylvania Convention Center

Session Description

Immunofluorescence and immunohistochemistry have long been essential to evaluation of both clinical kidney biopsies and as a research tool. This session explores recent advances in immunofluorescence and immunohistochemistry that allow for improved detection of monotypic deposits and assessment of complement activation in clinical kidney biopsy. Advances in research applications of immunofluorescence, including the use of artificial intelligence (AI) and highly multiplexed forms of immunofluorescence, are also highlighted.

Learning Objective(s)

  • Outline specialized immunofluorescence techniques to establish clonality and unmask potential monotypic deposits
  • Explain the role of staining for complement in kidney biopsies and as a biomarker of disease activity
  • Assess future potential applications of AI to immunofluorescence microscopy
  • Articulate the utility of highly multiplexed forms of immunofluorescence as a tool for identifying potential novel targets for therapy

Learning Pathway(s)

  • Pathology