Kidney Week

Translational Session

Membranous Nephropathy: From Science to Personalized Patient Care

November 08, 2025 | 04:30 PM - 06:00 PM

Location: General Assembly A, Convention Center

Session Description

This session presents the latest developments in membranous nephropathy (MN) from three perspectives: research, diagnosis, and management. Recent scientific research is highlighted with a focus on disease pathogenesis: the responsible antigens, autoimmunity, complement activation, and mechanisms of podocyte injury. The connection between experimental work and clinical patient care is discussed. Topics in diagnosis and histopathology emphasize how kidney biopsy can inform clinical care. Clinical management and use of biomarkers to guide treatment of MN are discussed.

Learning Objective(s)

• Describe the major pathophysiological steps in MN
• Summarize relevant research studies in MN that affect clinical care
• Discuss the diagnostic approach to MN and the ways in which kidney biopsy can guide management
• List major clinical studies investigating first-line therapeutics for MN and describe ongoing or planned clinical trials for novel agents
• Explain how longitudinal monitoring of biomarkers can guide management of MN

Learning Pathway(s)

• Glomerular Diseases

Moderators

• Dhruti P. Chen, MD
• Patrick H. Nachman, MD, FASN

Presentations

• Pathogenesis of Membranous Nephropathy: Underlying Science and Its Impact on Patient Care
  04:30 PM - 04:50 PM
  
  • Elion Hoxha, MD

Pathogenesis of Membranous Nephropathy: Underlying Science and Its Impact on Patient Care

November 08, 2025 | 04:30 PM - 04:50 PM

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• Noninvasive or Invasive Diagnosis? Why We Still Need Kidney Biopsies in Membranous Nephropathy
  04:50 PM - 05:10 PM
  
  • Tiffany Caza, MD, PhD

Noninvasive or Invasive Diagnosis? Why We Still Need Kidney Biopsies in Membranous Nephropathy

November 08, 2025 | 04:50 PM - 05:10 PM

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• Management of Membranous Nephropathy: Biomarkers and a Personalized Medicine Approach to Therapy
  05:10 PM - 05:30 PM
  
  • Laurence H. Beck, MD, PhD

Management of Membranous Nephropathy: Biomarkers and a Personalized Medicine Approach to Therapy

November 08, 2025 | 05:10 PM - 05:30 PM

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• Membranous Nephropathy: New Treatments on the Horizon
  05:30 PM - 05:50 PM
  
  • Pierre M. Ronco, MD, PhD

Membranous Nephropathy: New Treatments on the Horizon

November 08, 2025 | 05:30 PM - 05:50 PM

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• Q&A
  05:50 PM - 06:00 PM
  

Q&A

November 08, 2025 | 05:50 PM - 06:00 PM

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