Kidney Week

Basic/Clinical Science Session

Novel Immune Modulators of Allograft Rejection

November 06, 2025 | 02:00 PM - 04:00 PM

Location: Grand Ballroom C, Convention Center

Session Description

During allogeneic kidney transplantation, immune cells infiltrate renal allografts and promote both T cell-mediated and antibody-mediated rejection. This session explores novel mechanisms that control immune cell behavior in renal allografts and therefore influence both T cell-mediated and antibody-mediated rejection.

Learning Objective(s)

• Explain how the stromal cell landscape changes during rejection of renal allografts
• Explain how monocytes/macrophages modulate transplant tolerance
• Define the role of glycoproteins in kidney transplantation
• Describe novel approaches to the study of specific antibody glycosylation and its functional effects

Learning Pathway(s)

• Kidney Transplantation

Moderators

• Naoka Murakami, MD, PhD, FASN
• Hamid Rabb, MD, FASN

Presentations

• Modulation of Rejection via T and B Cell Interaction with Intrarenal Stromal Cells
  02:00 PM - 02:30 PM
  
  • Peter Sage, PhD

Modulation of Rejection via T and B Cell Interaction with Intrarenal Stromal Cells

November 06, 2025 | 02:00 PM - 02:30 PM

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• Role of Monocytes/Macrophages in Transplant Tolerance
  02:30 PM - 03:00 PM
  
  • Xun-Rong Luo, MD, PhD, FASN

Role of Monocytes/Macrophages in Transplant Tolerance

November 06, 2025 | 02:30 PM - 03:00 PM

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• Role of Glycoproteins in Antibody-Mediated Rejection in Kidney Transplantation
  03:00 PM - 03:30 PM
  
  • Ana Konvalinka, MD, PhD

Role of Glycoproteins in Antibody-Mediated Rejection in Kidney Transplantation

November 06, 2025 | 03:00 PM - 03:30 PM

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• Limiting Rejection via Defensive Tolerance in Kidney Allografts
  03:30 PM - 04:00 PM
  
  • Alessandro Alessandrini, PhD

Limiting Rejection via Defensive Tolerance in Kidney Allografts

November 06, 2025 | 03:30 PM - 04:00 PM

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