Basic/Clinical Science Session
Decoding AKI: The Omics Revolution
November 08, 2025 | 02:00 PM - 04:00 PM
Location: Room 362A, Convention Center
Session Description
New technologies such as spatial transcriptomics and Dyna-vivo-seq have enabled tracking real-time gene expression changes at the single-cell level. These technological breakthroughs, combined with proteomic analysis, have uncovered how kidney tubular cells adapt to injury and orchestrate repair mechanisms, providing a comprehensive landscape at the molecular level. This session reviews and discusses crucial insights into kidney injury and repair and advances understanding of renal pathophysiology.
Learning Objective(s)
- Discuss the power of RNA sequencing technology in discovering molecular mechanisms of injury and repair
- Describe the transcriptional re-programming that occurs during host and microbe interactions
- Identify dynamic changes in tubular gene expression patterns following a massive glomerular protein filtration load
- Describe the proteomic landscape of injured kidneys
Learning Pathway(s)
- AKI and Critical Care
- Kidney Biology and Physiology
Moderators
Presentations
- AKI to CKD Transition Viewed Through the Spatial Lens
02:00 PM - 02:30 PM
- Host-Microbial Interplay in the Kidneys
02:30 PM - 03:00 PM
- Spatiotemporal Landscape of the Tubule in Response to Glomerular Proteinuria
03:00 PM - 03:30 PM
- Proteomic Landscape of Injured Kidneys
03:30 PM - 04:00 PM