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To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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Kidney Week

ASN / Education & Meetings / Kidney Week /

Basic/Clinical Science Session

Post-Transcriptional and Post-Translational Processing in Glomerular Diseases

November 06, 2025 | 02:00 PM - 04:00 PM

Location: General Assembly A, Convention Center

Session Description

This session defines the roles of post-transcriptional processing, such as RNA alternative splicing, polyadenylation, miRNA function, and lncRNA functions, in glomerular disease pathophysiology. The roles of post-translational modifications are described, such as glycosylation and sumoylation in diseases such as FSGS, IgA nephropathy, and diabetic kidney disease (DKD).

Support for all sessions in the Glomerular Diseases Learning Pathway is provided by an educational grant from Vera Therapeutics, Inc.

Learning Objective(s)

  • Describe the role of alternative splicing and polyadenylation in glomerular disease pathophysiology
  • Describe the role of miRNAs and lncRNAs in glomerular disease pathophysiology
  • Describe the role of glycosylation in glomerular disease pathophysiology
  • Describe the role of sumoylation in glomerular disease pathophysiology

Learning Pathway(s)

  • Glomerular Diseases
  • Diabetic Kidney Disease

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