Basic/Clinical Science Session
Post-Transcriptional and Post-Translational Processing in Glomerular Diseases
November 06, 2025 | 02:00 PM - 04:00 PM
Location: General Assembly A, Convention Center
Session Description
This session defines the roles of post-transcriptional processing, such as RNA alternative splicing, polyadenylation, miRNA function, and lncRNA functions, in glomerular disease pathophysiology. The roles of post-translational modifications are described, such as glycosylation and sumoylation in diseases such as FSGS, IgA nephropathy, and diabetic kidney disease (DKD).
Learning Objective(s)
- Describe the role of alternative splicing and polyadenylation in glomerular disease pathophysiology
- Describe the role of miRNAs and lncRNAs in glomerular disease pathophysiology
- Describe the role of glycosylation in glomerular disease pathophysiology
- Describe the role of sumoylation in glomerular disease pathophysiology
Learning Pathway(s)
- Glomerular Diseases
- Diabetic Kidney Disease
Moderators
Presentations
- miRNAs and lncRNAs in DKD
02:00 PM - 02:30 PM
- mRNA Alternative Splicing and Polyadenylation Regulates the Slit Diaphragm in Glomerular Diseases
02:30 PM - 03:00 PM
- Association of Glycosylation of Serum IgA with IgAN and Glomerular Function
03:00 PM - 03:30 PM
- SUMOylation of Podocin Reverses the Progression of DKD
03:30 PM - 04:00 PM