ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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Kidney Week

Basic/Clinical Science Session

Immunity, Autoimmunity, and Hypertensive Kidney Damage

November 07, 2025 | 02:00 PM - 04:00 PM

Location: Grand Ballroom B, Convention Center

Session Description

This session delves into the intricate interplay between the immune system and inflammatory mediators and their role in the progression of target-organ damage in cardiovascular and kidney diseases. Leading experts present findings on how immune cell-specific angiotensin-receptor signaling contributes to hypertension, fibrosis, and organ damage. Discussions include the impact of cytokines on blood pressure regulation, end-organ injury, and sodium transporter activity, as well as their role in autoimmune nephritis.

Learning Objective(s)

  • Analyze the role of type 1 angiotensin receptors in specific immune-cell populations in driving hypertension, target-organ damage, and tissue fibrosis
  • Explain how cell-specific inflammatory cytokines regulate blood pressure, contribute to end-organ injury, and influence sodium transporters in hypertension and kidney damage
  • Describe mechanisms of autoimmune nephritis and the role of inflammatory mediators in the progression of kidney injury in cardiovascular diseases

Learning Pathway(s)

  • Hypertension and Cardiorenal Disorders

Moderators

Presentations