Basic/Clinical Science Session
Extending Glomerular Function in Aging
November 07, 2025 | 02:00 PM - 04:00 PM
Location: General Assembly A, Convention Center
Session Description
The aging population continues to increase worldwide. Kidney function decreases with age due to nephron loss. The loss of postmitotic podocytes and reduced endothelial nitric oxide activity are thought to be contributors to this process. Understanding the molecular mechanism that leads to glomerular aging can guide the development of therapeutic interventions that delay the process of age-related declines in kidney function. This session explores the current state of research developments focused on extending glomerular function, as well as emerging questions in this space.
Learning Objective(s)
- Explain the mechanisms involved in healthy and accelerated kidney aging
- Describe recently uncovered culprit drivers of accelerated aging in glomeruli and evolving approaches for slowing aging and extending glomerular function
- Assess the impact of aging on the function of the glomerular filtration barrier and identify opportunities for intervention
Learning Pathway(s)
- Glomerular Diseases
- CKD Non-Dialysis
Moderators
Presentations
- Age-Dependent Mitochondrial Function in Podocytes
02:00 PM - 02:30 PM
- Glomerular Endothelial Cells in Aging-Related Glomerular Filtration Barrier Dysfunction
02:30 PM - 03:00 PM
- Glycogen Synthase Kinase-3 Beta and the Aging Glomerulus
03:00 PM - 03:30 PM
- Reversing the Aged Phenotype
03:30 PM - 04:00 PM