ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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Kidney Week

Educational Symposium

Breaking Barriers: Advances in Understanding and Treating Complement-Mediated Kidney Disease

November 06, 2025 | 12:45 PM - 01:45 PM

Location: Room TBD2, Hilton Americas-Houston

Session Description

This engaging symposium explores the latest breakthroughs in the pathophysiology and treatment of complement-mediated kidney diseases (CMKDs), including IgA nephropathy (IgAN) and C3 glomerulopathy (C3GN). Leading experts discuss the intricate role of the complement system in disease progression, emerging biomarkers for early diagnosis, and cutting-edge complement-targeted therapies that are reshaping the treatment landscape. Participants gain valuable insights into novel therapeutic strategies, clinical trial updates, and the evolving precision medicine approach in these diseases.

Support is provided by an educational grant from Novartis Pharmaceuticals Corporation.

Learning Objective(s)

  • Describe the role of the complement system in the pathophysiology of CMKDs, including IgAN and C3GN, and its impact on disease progression
  • Assess the latest advancements in complement-targeted treatments, including novel inhibitors and biologic agents, and their potential to improve clinical outcomes for patients with CMKDs
  • Discuss the integration of complement biomarkers and individualized treatment strategies to optimize the diagnosis and management of patients with IgAN and C3GN

Learning Pathway(s)

  • Glomerular Diseases

Moderator

Presentations