RE: Help with hypercalcuria/hyperoxaluria case. 1 hour ago

As to the question "Can diet alone cause urine oxalate this high?", the answer is yes. Along with vitamin C, as pointed out by Roger, overconsumpti...

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RE: Help with hypercalcuria/hyperoxaluria case. 2 hours ago

? secondary hyperoxaluria from occult ileal disease... does she have chronic diarrhea vit B12 level ------------------------------ Jonathan Slater ...

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RE: A case of rpgn 2 hours ago

Further information Creatinine fluctuated between 3.5-3.8mg/dl Hep b, c and hiv all negative  V don't hav the facility for electron microscopy and ...

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RE: A case of membranous nephropathy in a 10 year old child 2 hours ago

"I think the original classification as primary versus secondary MN is a bit over and we better classify MN entities based on antigen serology or b...

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RE: Secondary hypertension Work up 3 hours ago

Please do let us know how he responded to increasing doses of spironolactone. ------------------------------ K.K. Venkat MD Troy MI (248) 420 7798 ...

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RE: A case of membranous nephropathy in a 10 year old child 3 hours ago

OK, this suggests that the signal by anti-PLA2R ELISA was non-specific. I suppose the result by indirect fluorescence was done at a low dilution, t...

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RE: FSGS case 5 hours ago

I actually gave pulse methypred for 3 days, and continued high dose oral steroids, which had significant toxicity and patient wanted to stop it.  I...

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RE: Influenza Vaccine After Rituximab 5 hours ago

Thanks Dr. Rodby, can you provide the full version, I don't have access to NEJM journal watch.  Meanwhile, searching for other evidence I found tha...

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RE: Help with hypercalcuria/hyperoxaluria case. 6 hours ago

" Do you think diet alone could cause such a high urine oxalate?" You have to probe. See my list above. People eat oddly and can get into oxalate t...

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RE: A case of membranous nephropathy in a 10 year old child 7 hours ago

The PLA2R antibody was negative when tested by indirect immunofluorescence. Can we now disregard the PLA2R completely and call this a secondary mem...

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RE: Help with hypercalcuria/hyperoxaluria case. 9 hours ago

I have run across a few published cases of urinary oxalate Excretion of > 200 mg/gm creatinine that were entirely to very high oxalate in diet, “cu...

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RE: Help with hypercalcuria/hyperoxaluria case. 10 hours ago

I agree -a 24 hour urines oxalate of 130mg is very high, but might be attained by a huge dietary load, such as mega doses of ascorbic acid or powde...

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RE: Help with hypercalcuria/hyperoxaluria case. 11 hours ago

Thank you for your response. Do you think diet alone could cause such a high urine oxalate? ------------------------------ Jennifer Waldmann MD Fel...

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RE: Hypokalemia In A Young Woman. 15 hours ago

Second set of labs. --------------------------------- Ahlim Al sanani MD, MS Fellow Marshall University SOM Barboursville WV -------------------...

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RE: A case of rpgn 15 hours ago

Dr. Venkat- I suppose there is room to broaden the definition of RPGN as you suggest, but most authoritative sources link RPGN (the clinical syndro...

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RE: A case of rpgn 16 hours ago

Although the terms RPGN and crescentic GN are commonly used synonymously, the former refers to clinical course of a patient with a glomerular disea...

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RE: Help with hypercalcuria/hyperoxaluria case. 17 hours ago

Additional thoughts- a bone marrow biopsy will be very interesting. Extensive CaOx crystalline deposits in bone marrow and bone surfaces have been ...

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RE: help with patient with adpkd 17 hours ago

The problem with listing for deceased donor transplant without native nephrectomy first is that a zero-HLA-mismatch kidney may become available unp...

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RE: Help with hypercalcuria/hyperoxaluria case. 17 hours ago

You might want to inquire concerning excessive Vitamin C intake and Turmeric consumption, along with high fat intake - all common causes of hyper-o...

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RE: Help with hypercalcuria/hyperoxaluria case. 19 hours ago

Agree wholeheartedly. High-fat ketogenic diets can cause enteric hyper-oxaluria, IMO. Sent from my iPad

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RE: Influenza Vaccine After Rituximab 19 hours ago

good point https://www.jwatch.org/oh201201100000005/2012/01/10/rituximab-blocks-influenza-vaccine-response ------------------------------ Roger Rod...

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RE: A case of rpgn 19 hours ago

We really do not know how rapidly the GFR is decreasing in this case, since only a single serum creatinine was posted. This might be acute GN, but ...

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RE: Help with hypercalcuria/hyperoxaluria case. 19 hours ago

take a good Vit C and dietary history: from my oxalate data base ------------------------------ Roger Rodby MD, FASN Professor of Medicine Rush...

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RE: A case of rpgn 19 hours ago

This is not crescentic RPGN.. However, if SCr is rapidly increasing/GFR rapidly worsening, it will qualify clinically to be called RPGN. Except for...

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RE: Influenza Vaccine After Rituximab 19 hours ago

But how often is it effective in such patients. We Really don’t know, but this can’t be a reason for not giving it in the first place, IMO. Sent fr...

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RE: pt on ICPi with AKI 19 hours ago

The zometa associated cases I've seen is often subacute and that's why it takes so long to detect it.  However, in a couple of cases where we happe...

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RE: Influenza Vaccine After Rituximab 19 hours ago

All of our chemotherapy patients get the high dose flu vaccine. ------------------------------ Nelson Leung MD Mayo Clinic Rochester MN (507) 266-7...

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Help with hypercalcuria/hyperoxaluria case. 20 hours ago

I have a case that is puzzling me... 74yo F with hx afib, gout, DM, nephrolithiasis, who i have been following for over 2 years now. her 24 hr urin...

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RE: Secondary hypertension Work up 21 hours ago

the usual nightmare of working up for primary hyperaldo.  I'm not impressed by either the renin or aldo, But he does have hypoK and a metabolic alk...

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RE: Secondary hypertension Work up 23 hours ago

thanks. I was thinking about CTA too, but his Cr is high. I understand our rethinking regarding contrast induced nephropathy, but I don't think he ...

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RE: Secondary hypertension Work up 23 hours ago

Suspect renin and aldosterone levels on multiple drugs especially Lisinopril will be hard to interpret so if you really believe he is adherent (I r...

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RE: Secondary hypertension Work up 23 hours ago

I just saw him for the first time. Those studies were done a couple of months ago as in-patient when he was admitted for 'stroke rule out'. I am no...

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RE: help with patient with adpkd 23 hours ago

So agree that decision regarding preemptive nephrectomy with possible need for dialysis vs simultaneous native nephrectomy should be coordinated wi...

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RE: NS in a patient of psoriasis 1 day ago

Some patients who do not respond to tacrolimus do respond to cyclosporine. This is mostly in children and experience in adults would be more guarde...

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RE: A case of rpgn 1 day ago

What is the patients HIV/HCV/HBV status? Do you have any EM Studies? Without crescents this is not RPGN. Could be infection related GN. Sent from m...

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RE: A case of rpgn 1 day ago

Initially I thought you were going to allude to a thrombotic microangiopathy given the high blood pressure.   But then I read the biopsy and saw 2+...

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RE: NS in a patient of psoriasis 1 day ago

Before subjecting the patient to another biopsy, detailed reevaluation of the first biopsy by an experienced renal pathologist is warranted. Also, ...

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RE: Renal cysts and Erthryocytosis 1 day ago

There is a large experience of using an ACE-I or ARB to treat post-renal transplant erythrocytosis which is attributed mostly to continued EPO prod...

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RE: Renal cysts and Erthryocytosis 1 day ago

Thanks for all this input! I'm pulling the imaging reports but he was told quite clearly they were simple cysts.  Of course, if complex, I would ch...

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RE: Graft Dysfunction ? TMA 1 day ago

We had a patient once who was treated elsewhere and had TMA on biopsy done for graft dysfunction. Creatinine was around 2.5 to 3 for about 2-3 mont...

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RE: Pregnant patient with Liddle syndrome 1 day ago

Does family history reveal autosomal dominance for hypertension? In addition to amiloride for hypertension should gene analysis be done? ----------...

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A case of rpgn 1 day ago

21 yr male, presented with recent onset of hypertension with renal impairment. No significant clue in history suggestive of any specific disorder. ...

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RE: Crescentic IgA Nephropathy 1 day ago

Sorry. Meant advisable not available. ------------------------------ K.K. Venkat MD Troy MI (248) 420 7798 ------------------------------

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RE: help with patient with adpkd 1 day ago

Up to 6 months of pretransplant dialysis is probably same as a preemptive transplant in terms of long-term post-transplant outcomes. The choice of ...

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RE: Secondary hypertension Work up 1 day ago

I am always skeptical of adherence in pts with poorly controlled HTN on multiple antihypertensive agents. Brief hospitalization usually will clarif...

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RE: Renal cysts and Erthryocytosis 1 day ago

The question of whether a cyst or many cysts (as in polycystic kidneys) are associated with increased renal erythropoietin production has long been...

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RE: Hypokalemia In A Young Woman. 1 day ago

Which urine sample was chloride 41? ------------------------------ [Mark] [Lerman] [MD,FASN,FACP,FAST] [Past Medical Director Kidney Pancreas Trans...

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RE: NS in a patient of psoriasis 1 day ago

In general, both CYC and RTX gave little effect in steroid unresponsive FSGS. It woukd help to have a report on the LM, IF, EM findings. Sent from ...

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RE: excess urine output of uncerain etiology 1 day ago

If the “spot” uOSM is representative of a 3.2L daily urine volume, then tge daily OSM excretion rate is about 1000mOSM- and tge polyuria us largely...

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RE: NS in a patient of psoriasis 1 day ago

I assume mtx has been stopped? Steroid resistant NS thought to be MCD ( but may be FSGS). This degree of nephrosis makes me think this is primary f...

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