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To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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Orson W. Moe, MD, BRCU Faculty

Dr. Moe is a Professor of Internal Medicine and Physiology at the University of Texas Southwestern Medical Center. He serves as the Director of the Charles and Jane Pak Center for Mineral Metabolism and Clinical Research. He participates in education, clinical practice, clinical and basic research, and administration. His research is on renal physiology, mineral metabolism, and epithelial biology. His disease-oriented research is focused on nephrolithiasis, electrolyte disorders, extrarenal complications of chronic kidney disease and metabolic bone disorders. Moe is active in education locally, nationally, and internationally. He co-edits the textbook Seldin and Giebisch's The Kidney: Physiology and Pathophysiology, and Current Opinions of Nephrology and Hypertension, Pathophysiology section. He is a member of the American Association of Physicians, American Society of Clinical Research, American Physiologic Society and International Society of Nephrology.

Current Position/Titles:

Professor of Internal Medicine, Physiology, and Mineral Metabolism

Degrees/Training:

M.D., University of Toronto, Toronto, Ontario, Canada

Surgery Internship, Surgery, University of Toronto, St. Michael's Hospital, Toronto, Canada

Internal Medicine Residency: University of Toronto, Toronto, Ontario, Canada

Nephrology Fellowship: University of Toronto. Toronto, Ontario, Canada

Research/Post-Doc Training: University of Texas Southwestern Medical Center, Dallas, TX, USA

ASN Service:

Member ASN 1986-present, Organizer and Lecturer: ASN Minicourse Molecular Biology for Clinician 1994, Organizer and Lecturer: ASN Minisymposium Physiology meets Molecular Biology 1997, Organizer and Lecturer: ASN Workshop Basic Science for Clinical Nephrologist 1996-1998, 2002, Evaluating Committee for John P. Peters Award 2006-2009, Editorial Board J Am Soc Nephrology 2009-2017, Nominating Committee for Executive Council 2010-2011, Nominating Committee for Council at Large 2019-2020, Reviewer of ASN Meeting Abstracts: 1991, 1993, 1998, 2002, 2005- 2008, 2010-2013, 2015, 2017, 2020, 2023, ASN Abstract Section Chair: 2000, 2004, 2014, 2016, 2019

Leadership positions:

Chief of Nephrology, UT Southwestern Medical Center, 2014-2021

Director: Charles and Jane Pak Center for Mineral Metabolism and Clinical Research 2002-2020, 2020-2026 (Departmental status)

Director: UT Southwestern Nephrology T32 Training Program 2013-2021

O’Brien Kidney Research Center UT Southwestern 2013-2020

Honors:

Donald W. Seldin Professorship in Clinical Investigation 2002-present, Charles Pak Distinguished Chair in Mineral Metabolism Research 2002-present, Outstanding Freshman Teacher (Medical School) 2005-2006, 2010-2011, Notable of Physiology Teacher (Graduate School) 2012, ASN Jack Coburn Award and Lecture 2013, David Burton Rose Lectureship and Award (Inaugural) NYU 2015, Suk-Ki Hong Lectureship and Award SUNY Buffalo 2017, Donald W. Seldin Endowed lectureship and Award ASN 2018, Shaul Massry Lectureship and Award USC 2020, Donald W. Seldin Award and Lectureship AHA 2022

Board Certification:

Internal Medicine, Nephrology

Research Interests:

My research is on basic renal physiology and pathobiology of renal disease. My original training and interests were in epithelial ion transport, particularly Na+, H+, and phosphate. My recent foci have gravitated towards AKI, CKD, and extrarenal complications of CKD; especially how mineral disturbances act as mediators of CKD progression and uremic cardiovascular disease, the leading killer of renal patients. Our studies spans from humans, animal models, cells, and single molecules. Recent efforts have gravitated towards developing therapeutics that will eventually be translated to human applications.

Personal Statement:

I have dedicated four decades to academic nephrology in patient care, education, research and academic administration. I have maintained an active practice in inpatient nephrology and an outpatient referral practice. I am active in teaching graduate students medical students, residents and renal fellows at the national and international levels. I am active in editing journal and textbooks such as Seldin and Giebisch’s The Kidney: Physiology and Pathophysiology. My research originates from renal physiology and extends into disease-relevant pathophysiology. I have assumed numerous academic administrative leadership positions. I am ready to serve and contribute to the ASN in the at-large council.