Abstract: TH-PO1116

Prevalence of Hyponatremia in Dengue Infected Patients

Session Information

Category: Fluid, Electrolytes, and Acid-Base

  • 704 Fluid, Electrolyte, Acid-Base Disorders

Authors

  • Caputo, Daniel, Hospital Nacional Alejandro Posadas, El Palomar. Buenos Aires, Argentina
  • Negri, Armando Luis, Instituto de Investigaciones Metabólicas, Buenos Aires, Argentina
  • Ayus, Juan Carlos, Renal Consultants of Houston, Houston, Texas, United States
  • Eghi, Carlos, Hospital Posadas, Buenos Aires, Argentina
  • Cabral, Graciela Ester, Hospital Posadas, Buenos Aires, Argentina
  • Fernandez carreño, Ydania, Hospital Posadas, Buenos Aires, Argentina
Background

PHO-WHO (Dengue guidelines 2016), and CDC recommended high water intake in patients with dengue. However, no information exists about the prevalence of hyponatremia in newly infected patients.

Methods

Cross-sectional study in patients with newly diagnosed dengue infection in Argentina from January 2016 to April 2016. Hyponatremia was defined as serum sodium concentration <=135 mEq/L. Natremia was corrected in patients with hyperglycemia. Patients with creatinine greater a 1,6 mg/dl were excluded.

Results

We evaluated 146 patients with dengue diagnosis confirmed by IgM serology or PCR. Hyponatremia was present in 30.8% of the patients Figure 1. In the multivariate logistic regression model, the OR of hiponatremia adjusting for age and sex was significant in the group of over 65 years; OR 9.2 (IC95 2.9-28.9) p= 0,001. Figure 2

Conclusion

The prevalence of hyponatremia in newly infected patients with dengue, especially in older patients is high. Electrolyte evaluation should be done at admission in all patients with dengue and routine use of hypotonic fluids should be avoided in these patients.