Abstract: TH-PO528

Sociodemographic Trends in CKD Prevalence in the US

Session Information

Category: Chronic Kidney Disease (Non-Dialysis)

  • 307 CKD: Health Services, Disparities, Prevention

Authors

  • Vart, Priya, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States
  • Powe, Neil R., Priscilla Chan and Mark Zuckerberg San Francisco General Hospital & University of California SF, San Francisco, California, United States
  • McCulloch, Charles E., University of California San Francisco, San Francisco, California, United States
  • Saran, Rajiv, University of Michigan, Ann Arbor, Michigan, United States
  • Gillespie, Brenda W., University of Michigan, Ann Arbor, Michigan, United States
  • Saydah, Sharon, Centers for Disease Control and Prevention, Hyattsville, Alabama, United States
  • Shrestha, Sundar, Centers for Disease Control and Prevention, Hyattsville, Alabama, United States
  • Crews, Deidra C., Johns Hopkins University School of Medicine, Baltimore, Maryland, United States

Group or Team Name

  • CDC CKD Surveillance Team
Background

Overall prevalence of CKD in the U.S. has stabilized in recent years, however, whether this is true across sociodemographic groups is unknown. We examined trends in CKD prevalence by race/ethnicity, income (defined by poverty income ratio) and education using data from the population-based, cross-sectional National Health and Nutrition Examination Surveys (NHANES).

Methods

Participants >20 years with available creatinine were included. CKD prevalence was defined as eGFR 15 to <60 ml/min/1.73 m2 (CKD-EPI). NHANES data included for every 2 years from 2009-2014 (n range 4,869 to 5,662 per period). Unadjusted CKD prevalence was calculated for each sociodemographic group in each period. Interactions were tested between each sociodemographic group and survey period to assess trends. Adjusted [for age, sex, race/ethnicity (when not being examined)] relative risks were obtained comparing most vs. least disadvantaged category in each sociodemographic group for all periods 2009-2014.

Results

Adjusted CKD prevalence was higher in the most recent time period (2013-2014) for non-Hispanic whites (8.0%), Mexican-Americans (5.8%), poor (10.1%), high income (7.5%), 9-11th grade (8.4%) and some college/equivalent -educated persons (8.6%), as compared to earlier time periods for each specific group. Adjusted CKD prevalence among persons with <9th grade education fell to 7.9% in 2013-2014 (from 9.2% in 2011-2012). A statistically significant trend was only present for income (P for 6 year time trend of CKD prevalence was 0.2 for race, 0.03 for income and 0.3 for education). Adjusted relative risks for CKD prevalence are presented in the Table.

Conclusion

In recent years, CKD prevalence has increased in some sociodemographic groups, while decreasing in others.

Adjusted Relative Risk of CKD (95% CI) by Sociodemographic Group and Year
Group2009-20102011-20122013-2014
Non-Hispanic black vs. Non-Hispanic white1.3 (1.0-1.6)1.2 (0.9-1.5)0.9 (0.7-1.1)
Mexican American vs. Non-Hispanic white0.7 (0.4-0.9)0.7 (0.3-1.1)0.7 (0.4-1.1)
Poor vs. high income1.2 (0.7-1.6)1.3 (0.9-1.7)1.4 (0.7-2.0)
<9th grade vs. college education1.7 (1.2-2.2)1.4 (0.7-2.2)1.2 (0.6-1.8)

Funding

  • NIDDK Support