Abstract: SA-PO832

Effect of Physical Training on Echocardiographic Parameters during Hemodialysis: A Randomized Clinical Trial

Session Information

Category: Dialysis

  • 606 Dialysis: Epidemiology, Outcomes, Clinical Trials - Cardiovascular

Authors

  • Abundis Mora, Gabriela Jazmín, Hospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara, Mexico
  • Garcia-Garcia, Guillermo, Hospital Civil De Guadalajara, University of Guadalajara, Guadalajara, Mexico
  • Murillo brambila, Daniel, Hospital Civil De Guadalajara, University of Guadalajara, Guadalajara, Mexico
  • Jimenez cornejo, Monica Consuelo, Hospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara, Mexico
  • Renoirte, Karina, Hospital Civil de Guadalajara, Guadalajara, Mexico
  • Chavez, Jonathan, Hospital Civil de Guadalajara, Guadalajara, Mexico
Background

Patients on HD reduce their motor capacity over the time. It has been shown that physical training programs in HD are a safe intervention that positively impacts patients quality of life with positive effects on peak oxygen consumption, endothelial function and arterial stiffness index. Our objective was to evaluate the effect of a physical activity program with ergonomic bicycle during HD on the echocardiographic parameters of patients with conventional HD

Methods

Randomized, controled, unblinded clinical trial in prevalent HD patients, from september 2015 to may 2016, ≧18 years old. Patients with amputation of lower limbs, motor sequelae of cerebral vascular event and patients with vascular accesses in the lower extremities were excluded. Pre-dialysis biochemical test and echocardiographic parameters were taken at 0, 4 and 8 months.
The intervention group included 14 pts who performed 135 min per week of moderate intensity exercise with ergonomic bicycle for a period of 35 weeks. SPSS software version 2.0 was used.

Results

28 pts, average age 41 years, male (64%), HD vintage of 26 months. No difference was found in gender distribution, hereditary history, BMI, HbA1c, progression of CKD or hemodialysis time between the 2 groups.
In the intervention group there was an increase in deceleration time with a baseline value of 157 ms to 220 ms at 8 months, with a statistically significant result which was not observed in the control group. In the control group, there was an increase in PSAP with an initial value of 35 mmHg, which increased to 44.5 mmHg, with a statistically significant result.
Comparisons of biochemical level did not show statistically significant changes between both groups at 8 months of follow-up

Conclusion

HD pts with physical activity with an ergonomic bicycle for an 8-month period, compared against patients who did not perform physical activity, increased the deceleration time and did not increase PSAP.
Intradialytic aerobic exercise is a feasible way to improve the myocardial function of HD pts, however, the design of new studies is required to further explore the impact of this intervention on other vascular function markers and to determine whether or not it reduces cardiovascular morbidity and mortality observed in patients with CKD.