Abstract: TH-PO833

Functional Status among Patients Receiving Peritoneal Dialysis: Results from the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS)

Session Information

  • Peritoneal Dialysis - I
    November 02, 2017 | Location: Hall H, Morial Convention Center
    Abstract Time: 10:00 AM - 10:00 AM

Category: Dialysis

  • 608 Peritoneal Dialysis

Authors

  • Tennankore, Karthik K., Dalhousie/Nova Scotia Health, Halifax, Nova Scotia, Canada
  • Zhao, Junhui, Arbor Research Collaborative for Health, Ann Arbor, Michigan, United States
  • Karaboyas, Angelo, Arbor Research Collaborative for Health, Ann Arbor, Michigan, United States
  • Morgenstern, Hal, University of Michigan, Ann Arbor, Michigan, United States
  • Finkelstein, Fredric O., Yale University, New Haven, Connecticut, United States
  • Cheawchanwattana, Areewan, Khon Kaen University, Khon Kaen, Thailand
  • Pisoni, Ronald L., Arbor Research Collaborative for Health, Ann Arbor, Michigan, United States
  • Shen, Jenny I., LaBiomed at Harbor-UCLA, Torrance, California, United States
  • Perl, Jeffrey, St. Michael's Hospital, Toronto, Ontario, Canada

Group or Team Name

  • On behalf of PDOPPS patient support working group
Background

We have shown that high functional dependence among hemodialysis (HD) patients is associated with mortality. Little is known about functional status in peritoneal dialysis (PD) patients and its variation by country.

Methods

In our cross-sectional study of PD patients (PDOPPS 2014-17), functional status (FS) was assessed by self-reported patient questionnaire. Numerical scores were assigned to 8 instrumental and 5 basic activities of daily living, based on one’s ability to perform each activity with or without assistance. A summed FS score (range: 1.25-13) was calculated for each patient and categorized as <8 (functionally dependent), 8-<11, 11-<13, or 13 (independent).

Results

To date, 2405 enrolled patients have complete data on FS. The distribution of FS scores varied across countries; scores were lowest in Thailand and highest in Japan (Fig 1). Among patients with FS=13 (48%), mean age was 58 and 35% had diabetes. The 20% of patients with FS <11 were older and have more comorbidities; 68-97% were receiving some assistance with PD, compared to 11% with FS=13. Only 6% of PD patients but 14% of HD patients (Am J Kidney Dis. 2016;67(2):283-92) had FS scores <8; 48% of PD patients but only 36% of HD patients had scores of 13.

Conclusion

Differences in FS scores were observed across countries in the PDOPPS. These differences may have been influenced by regional differences in PD utilization (i.e. availability of PD assistance) or measurement error. FS scores are higher in PD patients than in previously studied HD patients, but future work will need to address the sources of these differences, how interventions for improving functional status might benefit PD patients and assess the outcomes of functionally dependent patients with the use of assisted PD.

Funding

  • Commercial Support