Abstract: SA-PO749

Dietary Sodium Intake and Clinical Outcomes in Hemodialysis Patients

Session Information

Category: Dialysis

  • 601 Standard Hemodialysis for ESRD

Authors

  • Morales, Antonio Rivera, Regional General Hosptial 46, Mexican Institute of Social Security, Guadalajara, Mexico, Guadalajara, Jalisco, Mexico
  • López lozano, Carlos alberto, University of Guadalajara, Guadalajara, Mexico
  • Báez lópez, Sandra Leticia, University of Guadalajara, Guadalajara, Mexico
  • Barbarín vázquez, Anel Victoria, University of Guadalajara, Guadalajara, Mexico
  • Soto-Vargas, Javier, Regional General Hosptial 46, Mexican Institute of Social Security, Guadalajara, Mexico, Guadalajara, Jalisco, Mexico
  • Topete reyes, Jorge fernando, Regional General Hosptial 46, Mexican Institute of Social Security, Guadalajara, Mexico, Guadalajara, Jalisco, Mexico
Background

Dietary sodium is thought to play a major role in the pathogenesis of hypertension, hypervolemia and mortality in hemodialysis patients. The evidence supporting daily dietary sodium intake of 2 g on hemodialysis is not strong. Our objective was to assess the relation between sodium intake and interdialytic weight gain, hyper and hypotension in hemodialysis sessions, and hospitalizations.

Methods

We included 70 patients receiving thrice-weekly hemodialysis treatment in this prospective observational study. The median follow up was 32.4 months (IQR 24.8-34.3). Available data included demographics, laboratory and clinical measures and details of the dialysis prescription. We examined the dietary sodium intake in a hemodialysis and inter dialytic day with 2-day diet diary-assisted recalls.

Results

There was a male predominance (62.9%). The mean age was 45 years (IQR 29-60.0). The median sodium intake in a hemodialysis day was 1144.5 mg (IQR 576.0-1905.5) and in no HD day of 1499.5 mg (IQR 877-2098.2). The dry weight assessed by impedance was 60.0 kg (IQR 50.4-66.5) the post HD weight was 62.5 kg (IQR 52.0-68.4),with a median ultrafiltration of 2.5 liters (IQR 2.0-3.5), only 24 (34.3%) of the patients were in theirs dry weight. 40 (57%) patients were hypertensive previous to the HD session, and 15 (21.4%) developed hypotension during HD session. There were a weak correlation between sodium intake on HD day and no HD day, with the average ultrafiltration (R2 0.362 and 0.261, p= 0.002 and 0.041 respectively), but no with the systolic or diastolic pressures before and after HD session. There were an inverse association between the amount of sodium intake and hospitalizations (p=0.026). There were no association between sodium intake and the difference of actual weight and dry weight, or the development of hypotension or hypertension.

Conclusion

We find an inverse association between the amount of sodium intake and the number of hospitalizations; however there were no association with interdialytic weight gain, hypertension or hypotension in this cohort of HD patients.