Abstract: FR-PO501

Weight Loss in Veterans with CKD after Enrollment in a Weight Management Program

Session Information

Category: Chronic Kidney Disease (Non-Dialysis)

  • 304 CKD: Epidemiology, Outcomes - Non-Cardiovascular

Authors

  • Desai, Niraj, Cleveland VAMC, Case Western Reserve University, Cleveland, Ohio, United States
  • Carter, Cameron D, VHA, Cleveland, Ohio, United States
  • Dobre, Mirela A., Case Western Reserve University, Cleveland, Ohio, United States
  • Shaheen, Khaldoon, Case Western Reserve University, Cleveland, Ohio, United States
  • Navaneethan, Sankar D., Baylor College of Medicine, Houston, Texas, United States
  • Rahman, Mahboob, Case Western Reserve University, Cleveland, Ohio, United States
Background

Though obesity is common in patients with CKD, interventions to reduce weight have not been well studied in this population. We examined the relationship between enrollment in a weight management program and weight loss across strata of eGFR.

Methods

We conducted a retrospective, observational analysis of patients enrolled in Managing Overweight/Obesity for Veterans Everywhere (MOVE!), a multidisciplinary weight management program within the Veteran’s Affairs Medical Centers. Mean weight loss, and change in BMI for MOVE! participants was calculated comparing baseline weight measured upon enrollment to final weight measured at the last visit to the program. A control group not enrolled in MOVE! was evaluated for weight change over a similar time period. Paired t testing was used to assess statistical significance.

Results

4935 veterans (age 59.5 +/- 9.4 yrs, weight 119.1 +/- 21.3 kg, BMI 37.4 +/- 6.5 kg/m2, 18% black, 67% diabetic) were enrolled in MOVE! between 2006 and 2011. Mean weight loss was 1.0 +/- 6.4 kg (p<0.001) and mean decrease in BMI was 0.33 +/- 2.1 kg/m2 (p<0.001) after an average of 7.6 +/- 11.4 visits to the program. In an age, gender, BMI and weight matched cohort (n =4795), mean weight loss was 0.05 +/- 4.7 kg (p=0.438) and mean decrease in BMI was -0.05 +/- 1.7 kg/m2 (p=0.68). Mean weight loss and decrease in BMI was similar for each stratum of eGFR in the intervention group (eGFR >90: 0.9 +/- 6.8 kg, 0.26 +/- 2.1 kg/m2; eGFR 60-89: 1.1 +/- 6.6 kg, 0.36 +/- 2.2 kg/m2; eGFR 45-59: 1.0 +/- 5.4 kg, 0.34 +/- 1.8; eGFR 30-44: 1.0 +/- 4.9 kg, 0.26 +/- 1.6 kg/m2, all p<0.001). In the matched cohort, weight loss and decrease in BMI did not occur in any of the eGFR subgroups.

Conclusion

Enrollment in a multidisciplinary weight management program is associated with a modest weight loss across all strata of GFR.