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Abstract: SA-PO788

Resistance Training Improves Muscle Strength and Maintained Physical Performance in Patients with Maintenance Hemodialysis

Session Information

Category: Dialysis

  • 601 Standard Hemodialysis for ESRD

Authors

  • Moriiyama, Yoshifumi, Nagoya kyoritsu hospital, Nagoya, Japan
  • Aratani, Sae, Nippon Medical School Hospital, Tokyo, Japan
  • Hara, Masahiko, Osaka City University Graduate School of Medicine, Osaka, Japan
  • Ishikawa, Hideaki, Konan Kosei Hospital, Konan, Japan
Background

It is reported that reduced muscle strength and physical performance are prevalent conditions in patients with maintenance hemodialysis, and deleterious changes in these parameters are associated with elevated mortality.

Methods

We provided 306 patients with 6-month resistance training program during hemodialysis. Primary outcome measures included muscle strength measured by handgrip (mean of right and left), percent knee extension muscle power to body weight (pKEMP-BW; mean of right and left), and physical performance measured by short physical performance battery (SPPB). Differences of these variables during 6-month were compared using Wilcoxon signed rank test.

Results

Median age was 71 (quartile 64-77) years old, 160 patients (52.2%) were men, and median dry weight was 54.5 (47.5-62.0) kg. During the 6-month, handgrip showed a slight increase in lower quartile from 22.8 (16.8-28.5) kg to 22.8 (18.3-28.5) kg (p<0.001), pKEMP-BW showed significant increase from 41.0 (32.0-51.8) % to 43.1 (34.4-54.7) % (p<0.001), and SPPB did not change the median and quartile values from 11.0 (9.0-12.0) to 11.0 (9.0-12.0) (Figure).

Conclusion

Resistance training improved muscle strength and maintained physical performance in patients with maintenance hemodialysis. We speculate that resistance training has a potential to prevent progression of sarcopenia and frailty in patients with maintenance hemodialysis.