Abstract: FR-PO877

The Present Status of Fatigue in Maintenance Hemodialysis Patients and Its Influencing Factors

Session Information

Category: Dialysis

  • 607 Dialysis: Epidemiology, Outcomes, Clinical Trials - Non-Cardiovascular


  • Zhuang, Bing, The second affiliated hospital of nanjing medical university, Nanjing, China
  • Yang, Junwei, Second Affiliated Hospital, Nanjing Medical University, Nanjing, China

Fatigue is a common and complex phenomenon in maintenance hemodialysis patients that significantly decreases the health-related quality of life, especially after hemodialysis treatment, frequently requiremore time to recover. The aim of this study was to analysis the fatigue status of hemodialysis patients in our dialysis center, explore the influencing factors of fatigue in these patients and proposeeffective intervention measures.


This study is a observational study. From June 2016 to February 2017,120 maintenance hemodialysis patients were enrolled the research in our center. The patients completed the questionnaires, including the Fatigue Assessment Scale(FAS) and the time of recovery from a dialysis session. The serum concentration of hemoglobin,albumin, electrolyte and the levels of PH, bicarbonate,lactic acidwere examined to statistics and analysis.


120 questionnaires were distributed and 111 were taken back, and 109 (90.8%) were effective among the questionnaires. The incidence of fatigue in maintenance hemodialysis patients was high, 63 of 109 (57.8%) patients enrolled in the study assessed of fatigue, 9.2% of patients had a severe fatigue. The time of recovery from hemodialysis (TIRD) is differently from 30 minutes to 24 hours. 66.1% of patients' recovery time was shorter than 2 hours, 29.3% was 2-12 hours, 4.6% of patients taked longer time to recover from a dialysis session. Most of them required more rest or sleep immediately after dialysis. The result of analysis is that the fatigue of patients was correlated with comorbidities (OR=0.202),the levels of lactic acid (OR=3.933) and the bicarbonate (OR=0.643) after dialysis. The rate of ultrafiltration,the levels of serum sodium and the levels of lactic acid after dialysis are different to the TIRD, the raised of lactic acid (OR=4.21) is associated of longer recovery time.


The incidence of fatigue patients in our dialysis center is more than a half,a few number of patients had a heavy fatigue,required more rest or sleep immediately after dialysis. The levels of lactic acid was the significant influencing factor of the fatigue in hemodialysis patients,TIRD was correlated with the raised of lactic acid during the dialysis process.


  • Government Support - Non-U.S.