Abstract: SA-PO057
Incidence and Outcomes of AKI in Octogenarians in Northern Jordan
Session Information
- AKI Clinical: Biomarkers and Dialysis
November 04, 2017 | Location: Hall H, Morial Convention Center
Abstract Time: 10:00 AM - 10:00 AM
Category: Acute Kidney Injury
- 003 AKI: Clinical and Translational
Authors
- Oweis, Ashraf Omar, Jordan University Of Science and Technology, Irbid, Jordan
- Alshelleh, Sameeha A., University Of Jordan, Amman, Jordan
Background
Due to improvements in the health care system worldwide, human life expectancy has increased, resulting in a greater number of geriatric patients diagnosed with acute kidney injury (AKI). We evaluated the incidence and outcome of AKI in octogenarians, as studies in this age group are few.
Methods
Design: Retrospective chart review.
Setting: The medical ward of our tertiary-care hospital in northern Jordan.
Participants: All patients aged 80-89 admitted to our medical ward between January 2010 and December 2013. Patients with stage IV and V chronic kidney disease were excluded.
Measurements: The incidence of AKI determined by the Acute Kidney Injury Network classification, mortality, and hospital length of stay.
Results
There were 850 patients admitted during the study period. Of these, 135 were excluded from our analysis. The most common admission diagnoses were uncontrolled diabetes mellitus and acute coronary syndrome. AKI occurred in 216 patients (30.2%). In these cases, Stage 1, Stage 2, and Stage 3 disease were present in 59%, 17.5%, and 23.5%, respectively. Of the 115 patients who died before discharge (16.1%), 87 (75.6%) had developed AKI. Hypertension, the use of angiotensin receptor blockers and non-steroidal anti-inflammatory drugs, heart failure, and exposure to radiologic contrast media were significant risk factors for AKI.
Conclusion
Appropriate management of diabetes and hypertension in octogenarians will likely decrease the incidence of AKI in this age group leading to reduced hospital length of stay and mortality.
Baseline characteristics
Variable | N (%) |
Gender, Male | 355 (49.6%) |
Female | 360 (50.4%) |
Diabetes mellitus | 115 (16.1%) |
Hypertension | 125 (17.5%) |
Coronary artery disease | 111 (15.5%) |
Congestive heart failure | 49 (6.9%) |
Cerebral vascular accident | 71 (9.9%) |
Peripheral vascular disease | 140 (19.9%) |
Cancer | 34 (4.8%) |
Angiotensin converting enzyme inhibitor | 191 (26.7%) |
Angiotensin receptor blockers | 110 (15.4%) |
Non-steroidal anti-inflammatory drugs | 20 (2.8%) |
Contrast | 153 (21.4%) |
Baseline creatinine, mean SD | 123.8 (105.5) |
Funding
- Government Support - Non-U.S.