Abstract: SA-PO057

Incidence and Outcomes of AKI in Octogenarians in Northern Jordan

Session Information

Category: Acute Kidney Injury

  • 003 AKI: Clinical and Translational

Authors

  • Oweis, Ashraf Omar, Jordan University Of Science and Technology, Irbid, Jordan
  • Alshelleh, Sameeha A., University Of Jordan, Amman, Jordan
Background

Due to improvements in the health care system worldwide, human life expectancy has increased, resulting in a greater number of geriatric patients diagnosed with acute kidney injury (AKI). We evaluated the incidence and outcome of AKI in octogenarians, as studies in this age group are few.

Methods

Design: Retrospective chart review.
Setting: The medical ward of our tertiary-care hospital in northern Jordan.
Participants: All patients aged 80-89 admitted to our medical ward between January 2010 and December 2013. Patients with stage IV and V chronic kidney disease were excluded.
Measurements: The incidence of AKI determined by the Acute Kidney Injury Network classification, mortality, and hospital length of stay.

Results

There were 850 patients admitted during the study period. Of these, 135 were excluded from our analysis. The most common admission diagnoses were uncontrolled diabetes mellitus and acute coronary syndrome. AKI occurred in 216 patients (30.2%). In these cases, Stage 1, Stage 2, and Stage 3 disease were present in 59%, 17.5%, and 23.5%, respectively. Of the 115 patients who died before discharge (16.1%), 87 (75.6%) had developed AKI. Hypertension, the use of angiotensin receptor blockers and non-steroidal anti-inflammatory drugs, heart failure, and exposure to radiologic contrast media were significant risk factors for AKI.

Conclusion

Appropriate management of diabetes and hypertension in octogenarians will likely decrease the incidence of AKI in this age group leading to reduced hospital length of stay and mortality.

Baseline characteristics
Variable
N (%)
Gender, Male355 (49.6%)
Female360 (50.4%)
Diabetes mellitus115 (16.1%)
Hypertension125 (17.5%)
Coronary artery disease111 (15.5%)
Congestive heart failure49 (6.9%)
Cerebral vascular accident71 (9.9%)
Peripheral vascular disease140 (19.9%)
Cancer34 (4.8%)
Angiotensin converting enzyme inhibitor191 (26.7%)
Angiotensin receptor blockers110 (15.4%)
Non-steroidal anti-inflammatory drugs20 (2.8%)
Contrast153 (21.4%)
Baseline creatinine, mean SD123.8 (105.5)

Funding

  • Government Support - Non-U.S.