Abstract: TH-PO976

Kidney Donor Risk Index Is a Good Prognostic Tool for Prediction of Early Post-Transplant Kidney Function and Graft Survival in a Korean Population

Session Information

Category: Transplantation

  • 1702 Transplantation: Clinical and Translational

Authors

  • Ro, Han, Gachon University Gil Medical Center, Incheon, Korea (the Republic of)
  • Han, Miyeun, SEOUL NATIONAL UNIVERSITY HOSPITAL, SEOUL, Korea (the Republic of)
  • Jeong, Jong Cheol, Ajou University Hospital, Suwon, Korea (the Republic of)
  • Jung, Ji Yong, Gachon University Gil Medical Center, Incheon, Korea (the Republic of)
  • Chung, Wookyung, Gachon University Gil Hospital Nephrology, Incheon, Korea (the Republic of)
  • Ahn, Curie, Seoul National University Hospital, Seoul, Korea (the Republic of)
Background

Kidney donor risk index (KDRI) is used in the United States to estimate the deceased donor kidney. However, KDRI is not yet used in Asian population. We tried to validate KDRI in assessment of deceased donor kidney in a large number of Korean population group.

Methods

The data of Korean Organ Transplantation Registry (KOTRY) between 2009 to 2012 was used in the analysis. Among 1924 deceased donor kidney transplantation, 1582 cases in which KDRI score could be calculated were included in this study. We investigate the impact of KDRI on the graft function and graft survival.

Results

We divided the donors by KDRI tertile (T1: range, 0.6432~1.17025, T2: range, 1.17057~1.48566, T3: range, 1.48630~3.80629). The recipients of T1 were younger and had less diabetes. Mean estimated glomerular filtration rate at post transplant 1 year of each group was 76.1 ±21.0, 64.7 ±20.3, 55.5 ± 21.0 ml/min/1.73m2 respectively. In the Cox regression analysis, KDRI showed good association with death censored graft survival, of which median follow up duration was 24.6 months (hazard ratio 1.778, 95% confidence interval 1.087-2.906, p=0.022).

Conclusion

KDRI is a good tool for estimation of early posttransplant outcomes in Korean population.

Funding

  • Government Support - Non-U.S.