Kidney Week

Abstract: TH-PO976

Kidney Donor Risk Index Is a Good Prognostic Tool for Prediction of Early Post-Transplant Kidney Function and Graft Survival in a Korean Population

Session Information

• Live Donor Outcomes and Kidney Transplantation in Pediatric and Ethnic/Racial Groups
  November 02, 2017 | Location: Hall H, Morial Convention Center
  Abstract Time: 10:00 AM - 10:00 AM

Category: Transplantation

• 1702 Transplantation: Clinical and Translational

Authors

• Ro, Han, Gachon University Gil Medical Center, Incheon, Korea (the Republic of)

Han Ro,

• Han, Miyeun, SEOUL NATIONAL UNIVERSITY HOSPITAL, SEOUL, Korea (the Republic of)

Miyeun Han,

• Jeong, Jong Cheol, Ajou University Hospital, Suwon, Korea (the Republic of)

Jong Cheol Jeong,

• Jung, Ji Yong, Gachon University Gil Medical Center, Incheon, Korea (the Republic of)

Ji Yong Jung,

• Chung, Wookyung, Gachon University Gil Hospital Nephrology, Incheon, Korea (the Republic of)

Wookyung Chung,

• Ahn, Curie, Seoul National University Hospital, Seoul, Korea (the Republic of)

Curie Ahn,

Background

Kidney donor risk index (KDRI) is used in the United States to estimate the deceased donor kidney. However, KDRI is not yet used in Asian population. We tried to validate KDRI in assessment of deceased donor kidney in a large number of Korean population group.

Methods

The data of Korean Organ Transplantation Registry (KOTRY) between 2009 to 2012 was used in the analysis. Among 1924 deceased donor kidney transplantation, 1582 cases in which KDRI score could be calculated were included in this study. We investigate the impact of KDRI on the graft function and graft survival.

Results

We divided the donors by KDRI tertile (T1: range, 0.6432~1.17025, T2: range, 1.17057~1.48566, T3: range, 1.48630~3.80629). The recipients of T1 were younger and had less diabetes. Mean estimated glomerular filtration rate at post transplant 1 year of each group was 76.1 ±21.0, 64.7 ±20.3, 55.5 ± 21.0 ml/min/1.73m² respectively. In the Cox regression analysis, KDRI showed good association with death censored graft survival, of which median follow up duration was 24.6 months (hazard ratio 1.778, 95% confidence interval 1.087-2.906, p=0.022).

Conclusion

KDRI is a good tool for estimation of early posttransplant outcomes in Korean population.

Funding

• Government Support - Non-U.S.