Abstract: TH-PO979

Correlation of Pre Kidney Transplant Psychosocial Factors with Post-Transplant Kidney Graft Survival

Session Information

Category: Transplantation

  • 1702 Transplantation: Clinical and Translational

Authors

  • Schreiber, Brittany Lauren, University of Texas Medical Branch, Galveston, Texas, United States
  • Noriega, Ramon, University of Texas Medical Branch, Galveston, Texas, United States
  • Gamilla-Crudo, Ann Kathleen N., University of Texas Medical Branch, Galveston, Texas, United States
  • Shah, Sujan P, University of Texas Medical Branch, Galveston, Texas, United States
  • Espinoza, Flor, University of Texas Medical Branch, Galveston, Texas, United States
  • Patankar, Rohan, University of Texas Medical Branch, Galveston, Texas, United States
  • Fischer, Wayne G, University of Texas Medical Branch, Galveston, Texas, United States
  • Mujtaba, Muhammad Ahmad, University of Texas Medical Branch, Galveston, Texas, United States
Background

Pretransplant psychosocial and nutritional factors are important aspects of kidney transplant evaluation as they may be associated with post-transplant outcomes; however there is scant data on this topic. The aim of the study was to determine the correlations between pretransplant, nonclinical and psychosocial factors to post-transplant kidney allograft survival.

Methods

We selected the following pre-transplant factors: race, gender, food stamp, marital relationship, family support, income status, insurer, education, Karnofsky score, history of depression, active clinical follow up, dialysis compliance,serum albumin level, history of substance abuse, distance from transplant center etc. One year kidney allograf survivalwas selected as an outcome. The study involved retrospective analysis of 131 kidney transplant patients. There were 56 female patients and 75 male patients. There were 56 female patients and 75 male patients. We had 72 Hispanics (53%), 33 African Americans (24%), 22 Whites (16%), 9 Asians (7%). Patients age ranged from 25 years to 77 years. Nominal logistic regression analysis and multinominal logistic regression analysis were used to identify the significant relationship between one dependent nominal variable and one or more continuous-level independent variables. A p-value of ≤ 0.05 was considered significant

Results

Female gender (p .02), active pre listing clinic follow up (p=0.04), stronger immediate family support(p=0.06), proximity to primary transplant center (p 0.0012), pre transplant nutrional status as evidenced by serum albumin >3.5 gm/dl, was associated with a better one year graft survival, however food stamps status (p 0.004), repeat transplant status (p 0.05) was associated with poor allograft survival. Remaining variable’s did not show a significant relationship.

Conclusion

Pretransplant psychosocial assessment is an important component of kidney transplant work up as it is associated with one year kidney allograft survival. More studies are needed to confirm our findings.