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Abstract: SA-PO763

Dialyzer Reuse in Prevalent Hemodialysis Patients: Mortality and Clinical Outcomes

Session Information

Category: Dialysis

  • 601 Standard Hemodialysis for ESRD

Authors

  • Murillo brambila, Daniel, Hospital Civil De Guadalajara, University of Guadalajara, Guadalajara, Mexico
  • Jimenez cornejo, Monica Consuelo, Hospital Civil De Guadalajara, University of Guadalajara, Guadalajara, Mexico
  • Renoirte, Karina, Hospital Civil De Guadalajara, University of Guadalajara, Guadalajara, Mexico
  • Abundis Mora, Gabriela Jazmín, Hospital Civil De Guadalajara, University of Guadalajara, Guadalajara, Mexico
  • Garcia-Garcia, Guillermo, Hospital Civil De Guadalajara, University of Guadalajara, Guadalajara, Mexico
Background

Dialyzers reuse has been a common practice in the US. In Mexico, economical restrains related to CKD have forced to seek cheaper options to provide RRT among ESRD patients. Thus, dyalizer reuse has become a common practice in most of the hemodialysis clinics across the country. It is regulated by the Ministry of Health. Previous studies have reported no difference in mortality among patients with dialyzer reuse versus one single use. The aim of this study was to evaluate the clinical implications of dialyzer reuse in prevalent HD patients from Jalisco, Mexico

Methods

A cross-sectional, multicenter study in prevalent hemodialysis patients in Jalisco. 2561 insured and uninsured patients conformed the national data base. Only patients who had a Kt/V ≥1.2 were included for analysis. Mortality, vascular access, clinical variables and laboratory values were compared among patients with reusable dialyzers and those with single use dialyzers.

Results

2561 patients were evaluated for analysis. Only 597 patients (23.3%) had a kt/v ≥ 1.2. Reuse of dialyzer was performed in 482 of them (80.7%). Average reuse was 5.5 times per dialyzer (range 1-12). Serum electrolite, creatinine, uric acid, albumine, PTH, iron kinetics, urea pre/post did not differ among both patients who underwent reuse of dialyzer vs those with one single use dialyzer.

Conclusion

Serum electrolite, creatinine, uric acid, albumine, PTH and iron kinetics did not differ among patients who underwent reuse of dialyzer vs those with one single use dialyzer. Hemoglobine, urea pre and post values were statistically better for patients with dialyzer reuse. Time to death and mortality did not differ among both groups.
Dialyzer reuse continues to be a controversial practice, but according these findings, it appears to be a safe. Further studies are needed to asses the long term clinical impact of this practice, since the financial panorama of CKD points to an urgent and generalized need to optimize economical resources in order to provide safe treatments to more patients at lower costs.