ASN's Mission

ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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Kidney Week

Clinical Practice Session

The Kidney-Brain Axis

November 07, 2019 | 02:00 PM - 04:00 PM

Location: 146 A/B, Walter E. Washington Convention Center

Session Description

Cognitive dysfunction is commonly recognized among patients on dialysis, with an expanding scientific literature aiding the understanding of possible mechanisms. This session discusses possible contributors, including preexisting vascular comorbidity, neural injury by uremic toxins, ischemic stress induced by fluid removal, and other unrecognized etiologies. The effects of hemodialysis and peritoneal dialysis are reviewed. Experts also discuss screening tools for cognitive impairment and potential treatments.

Learning Objective(s)

  • Identify the prevalence of cognitive dysfunction, screening tests, and differential diagnosis of brain-related pathology in the ESRD population
  • Describe the influence of fluid removal and ischemic injury on cognitive decline in patients with ESRD
  • Differentiate the effects of hemodialysis and peritoneal dialysis on cognitive decline
  • Describe possible mitigators and treatments, exercise, transplantation, and cognitive training for cognitive decline among patients on dialysis

Learning Pathway(s)

  • Dialysis


  • Rasheeda K. Hall, MD, MS, MBA
  • Daniel E. Weiner, MD, MS, FASN