Basic/Clinical Science Session

Modeling Human Kidney Development Using Organoids

November 07, 2019 | 10:30 AM - 12:30 PM

Location: 207, Walter E. Washington Convention Center

Session Description

In a short time, kidney organoid differentiation from stem cells has developed into a highly promising technology to generate complex kidney-like structures for studies of human development and disease. This session explores the current status of the field with emphasis on how accurately organoids reflect human kidney tissue structure. Discussion focuses on design goals for improved fidelity of these systems.

Learning Objective(s)

  • Describe the current status of kidney organoid differentiation
  • Discuss possible design paths to improved kidney organoid fidelity
  • Summarize the scope of applications possible with today’s technology

Learning Pathway(s)

  • Development and Pediatrics
  • Genetic Diseases of the Kidneys

Moderator(s)

  • Edward J. Kelly, PhD
  • Ryuji Morizane, MD, PhD

Presentations

  • Morphological and Genetic Design Targets for Organoid Development
    10:30 AM - 11:00 AM
    Andrew P. McMahon, PhD
  • Vascularization of Kidney Organoids
    11:00 AM - 11:30 AM
    Ton J. Rabelink, MD, PhD
  • The Extracellular Environment Required for Nephrogenesis
    11:30 AM - 12:00 PM
    Rachel Lennon, MBBS, PhD
  • Bioengineering Functional Kidney Tissue
    12:00 PM - 12:30 PM
    Jennifer A. Lewis, PhD