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ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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Kidney Week

Basic/Clinical Science Session

Multiple Hats of Intercalated Cells

November 04, 2021 | 10:00 AM - 12:00 PM

Location: On-Demand, Virtual Only

Session Description

Intercalated cells play a major role in the regulation of body acid-base homeostasis, but their role in the physiology and pathophysiology of the kidney goes much further. This session outlines the multiple functions and the complexity of intercalated cells. In addition to the latest information on their role in acid-base homeostasis, particular emphasis is given to their contribution to salt and potassium homeostasis and the more recently discovered functions that identify intercalated cells as sources of urinary antimicrobial peptides.

Learning Objective(s)

  • Describe how intercalated cells contribute to acid base homeostasis
  • Define the role of intercalated cells in the renal handling of salt
  • Explain the role of intercalated cells in the renal handling of potassium
  • Discuss the unique role of intercalated cells as sources of urinary antimicrobial peptides

Learning Pathway(s)

  • Cell and Transport Physiology
  • Chronic Kidney Disease

Moderators

  • L. Lee Hamm, MD
  • Oleg Palygin, PhD

Presentations

  • New Aspects of Acid-Base Regulation by Intercalated Cells
    10:00 AM - 12:00 PM
    Nuria M. Pastor-Soler, MD, PhD, FASN
  • Role of Intercalated Cells in Salt Homeostasis
    10:00 AM - 12:00 PM
    Susan M. Wall, MD
  • Role of Intercalated Cells in Potassium Homeostasis
    10:00 AM - 12:00 PM
    Rolando Carrisoza-Gaytan, PhD
  • Intercalated Cells Are a Primary Source of Urinary Antimicrobial Peptides
    10:00 AM - 12:00 PM
    John David Spencer, MD, FASN