ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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Kidney Week

Basic/Clinical Science Session

Microvascular Inflammation in Kidney Transplantation: An Unresolved Dilemma

November 03, 2023 | 02:00 PM - 04:00 PM

Location: Room 109, Pennsylvania Convention Center

Session Description

Microvascular inflammation (MVI) has been a long-recognized histologic feature in the diagnosis of antibody-mediated rejection. This session explores non-HLA causes of MVI and the utility of gene expression profiling and histologic scoring as prognostic tools.

ASN thanks the Renal Pathology Society for assistance with this session.

Learning Objective(s)

  • Explain how MVI can result from both antibody-dependent and antibody-independent mechanisms of endothelial injury
  • Discuss the clinical significance of MVI in the absence of positive donor-specific antibodies
  • Describe the importance of capillaritis as identified by gene expression profiling
  • Assess combinations of histologic findings, including MVI, in transplant outcomes

Learning Pathway(s)

  • Pathology
  • Kidney Transplantation