Kidney Week

Basic/Clinical Science Session

Microvascular Inflammation in Kidney Transplantation: An Unresolved Dilemma

November 03, 2023 | 02:00 PM - 04:00 PM

Location: Room 109, Pennsylvania Convention Center

Session Description

Microvascular inflammation (MVI) has been a long-recognized histologic feature in the diagnosis of antibody-mediated rejection. This session explores non-HLA causes of MVI and the utility of gene expression profiling and histologic scoring as prognostic tools.

ASN thanks the Renal Pathology Society for assistance with this session.

Learning Objective(s)

• Explain how MVI can result from both antibody-dependent and antibody-independent mechanisms of endothelial injury
• Discuss the clinical significance of MVI in the absence of positive donor-specific antibodies
• Describe the importance of capillaritis as identified by gene expression profiling
• Assess combinations of histologic findings, including MVI, in transplant outcomes

Learning Pathway(s)

• Pathology
• Kidney Transplantation

Moderators

• Surya V. Seshan, MBBS
• Kristen Tomaszewski, MD

Presentations

• Mechanisms of Microvascular Inflammation in the Kidney Allograft
  02:00 PM - 02:30 PM
  
  • Dany Anglicheau, MD, PhD
  Dany Anglicheau, MD, PhD

Mechanisms of Microvascular Inflammation in the Kidney Allograft

November 03, 2023 | 02:00 PM - 02:30 PM

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• Clinical Significance of Microvascular Inflammation: Are Donor-Specific Antibodies Required?
  02:30 PM - 03:00 PM
  
  • Chul Woo Yang, MD, PhD
  Chul Woo Yang, MD, PhD

Clinical Significance of Microvascular Inflammation: Are Donor-Specific Antibodies Required?

November 03, 2023 | 02:30 PM - 03:00 PM

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• Gene Expression Profiling in Microvascular Inflammation
  03:00 PM - 03:30 PM
  
  • Ivy A. Rosales, MD
  Ivy A. Rosales, MD

Gene Expression Profiling in Microvascular Inflammation

November 03, 2023 | 03:00 PM - 03:30 PM

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• Pathologic Scoring of Microvascular Inflammation: Importance in Diagnosis and Prognosis in Antibody-Mediated Rejection
  03:30 PM - 04:00 PM
  
  • Mark Haas, MD, PhD
  Mark Haas, MD, PhD

Pathologic Scoring of Microvascular Inflammation: Importance in Diagnosis and Prognosis in Antibody-Mediated Rejection

November 03, 2023 | 03:30 PM - 04:00 PM

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