Basic/Clinical Science Session
How to Combat AKI: Control Damage or Promote Repair?
November 06, 2025 | 02:00 PM - 04:00 PM
Location: Room 362A, Convention Center
Session Description
Treatment of AKI encompasses both prevention of damage and promotion of repair, with new research strategies focusing on reducing cell death through multiple pathways. Understanding the roles of DNA damage and organelle stress has provided critical insights into injury mechanisms, while emerging research into nerve activity modulation offers promising new solutions to treat AKI. This session reviews new understanding of cellular stress responses and neuromodulation during AKI and discusses novel therapeutic strategies to mitigate AKI.
ASN thanks the Japanese Society of Nephrology (JSN) and JSN Ambassador, Dr. Tsuyoshi Inoue.
Learning Objective(s)
- Identify current strategies to reduce cell death during AKI
- Explain the role of DNA damage and organelle stress response in kidney injury and repair
- Discuss new avenues to treat AKI, specifically focusing on nerve activity
Learning Pathway(s)
- AKI and Critical Care
- Kidney Biology and Physiology
Moderators
Presentations
- Targeting Cell Death in AKI
02:00 PM - 02:30 PM
- DNA Damage Repair in AKI
02:30 PM - 03:00 PM
- Organelle Stress During AKI
03:00 PM - 03:30 PM
- Optogenetic Rescue: A Bright Solution for Kidney Injury
03:30 PM - 04:00 PM