Basic/Clinical Science Session
Renin-Angiotensin System and Kidney Function: Mechanisms, Insights, and Implications
November 06, 2025 | 02:00 PM - 04:00 PM
Location: Grand Ballroom B, Convention Center
Session Description
This session explores cutting-edge research on the renin-angiotensin system (RAS) and its role in kidney function and pathology. Leading experts present new insights into the regulation of RAS components, their mechanosensory controls, and downstream effects on renal physiology. Discussions emphasize the mechanisms behind therapeutic interventions, potential unintended consequences, and emerging areas of discovery. Attendees gain a deeper understanding of RAS regulation and its impact on kidney health and diseases.
Learning Objective(s)
- Analyze how long-term therapy with RAS blockers affects renin-forming cells, underlying mechanisms, and potential undesirable consequences these adaptations may pose
- Describe the role of PIEZO2 and other mechanosensors in renin control, with insights into how mechanical forces influence RAS regulation and kidney function
- Assess the roles of angiotensin-converting enzyme 2 (ACE2) in kidney function and diseases, as well as mechanisms of epithelial sodium channel regulation independent of aldosterone
Learning Pathway(s)
- Hypertension and Cardiorenal Disorders
Moderators
Presentations
- Renin-Forming Cells After Long-Term Therapy with RAS Blockers
02:00 PM - 02:30 PM
- Renin Control by Mechanosensors: Role of PIEZO2
02:30 PM - 03:00 PM
- Angiotensin-Converting Enzyme 2 and Its Role in Kidney Function and Diseases
03:00 PM - 03:30 PM
- Angiotensin-Converting Enzyme 2 in Hypertension and Diabetic Kidney Disease
03:30 PM - 04:00 PM