Abstract: FR-PO822

Evaluation of Intradialytic Hypertension Using Bioelectrical Impedance Combined with Echocardiography in Maintenance Haemodialysis Patients

Session Information

Category: Dialysis

  • 601 Standard Hemodialysis for ESRD

Author

  • Ren, Hongqi, Jinling Hospital,Nanjing University School of Medicine, Nanjing, Jiangsu, China
Background

Although intra-dialytic hypertension(IDH) has been noted in clinical setttings for many years, its pathogenesis remains unclear. In this cross-sectional study, we aimed to analyze IDH incidence in our center and the correlation between postdialysis volume state and IDH.

Methods

131maintenance haemodialysis (MHD) patients were enrolled in our study with bioelectrical impedance (BIA) and echocardiography (ECG) recorded. Demographic data was collected and laboratory examination was conducted. The patients were grouped into four groups according to the changes of systolic blood pressure (SBP) between postdialysis and predialysis.

Results

The incidence of IDH was10.7%. The proportion of extracellular water to total body weight (ECW/TW) evaluated by BIA, in the IDH group was significantly higher than those of the other three groups both in pre-and post- dialysis comparison. In particular, postdialysis SBP was highest in the highest tertile interval of ECW/TW. In addition, left ventricular volume (LVV) in the IDH group was the highest among all four groups. By binary logistic analyses, we found that predialysis SBP, postdialysis ECW/TW and LVV were independent risk factors of intradialytic hypertension. When predicting the probability of ECW/TW combined with LVV, ROC curve showed a AUC (0.752, 95 % CI was 0.613-0.896 )was higher than the LVV and ECW/TW alone .

Conclusion

In this study, we found that the volume expansion of ECW and intravascular compartments after the dialysis measured by the combination of bioelectrical impedance and echocardiography in patients with MHD. Our study further showed that post-dialysis volume expansion is an important factor for the development of IDH.

Funding

  • Government Support - Non-U.S.