Abstract: SA-PO404

The Spectrum of CKD in China: A National Study Based on 64.7 Million Hospitalized Patients from 2010 to 2015

Session Information

Category: Chronic Kidney Disease (Non-Dialysis)

  • 302 CKD: Estimating Equations, Incidence, Prevalence, Special Populations

Authors

  • Huang, Yu-ming, Renal Division, Peking University First Hospital, Beijing, China
  • Xu, Damin, Renal Division, Peking University First Hospital, Beijing, China
  • Long, Jianyan, China Standard Medical Information Research Center, Shenzhen, China
  • Shi, Ying, China Standard Medical Information Research Center, Shenzhen, China
  • Zhang, Luxia, Renal Division, Peking University First Hospital, Beijing, China
  • Wang, Haibo, China Standard Medical Information Research Center, Shenzhen, China
  • Levin, Adeera, St. Paul's Hospital and University of British Columbia, Vancouver, British Columbia, Canada
  • Zhao, Ming Hui, Renal Division, Peking University First Hospital, Beijing, China
Background

Chronic kidney disease (CKD) is a significant public health burden worldwide. Previous studies demonstrate that diabetes exceeded glomerulonephritis and became the leading cause of CKD in China, but the transition of other causes was still unclear.

Methods

We utilized a national in-patients database covering 878 class 3 hospitals (which provide primary, secondary and tertiary care to nationwide patients) and involving 64.7 million adult patients from 2010 to 2015. The specific causes of CKD were extracted from International Classification of Diseases-10 codes of discharge diagnoses.

Results

Altogether 4.5% of hospitalized patients (1.8 million) were identified as having CKD, with an increased percentage from 2010 (3.7%) to 2015 (4.7%). Increasing trends of diabetic kidney disease and hypertensive kidney damage were observed from 2010 to 2015, especially for northern urban areas. The percentage of obstructive nephropathy also increased gradually and constituted an important cause of CKD for southern rural residents.

Conclusion

The spectrum of etiologies of CKD is changing in China, and varies over time and geographic regions.

Figure 1. Trend of subgroups among hospitalized patients with CKD from 2010 to 2015

Note: DKD, chronic kidney disease with diabetes; GN, CKD due to glomerulonephritis; HTN, hypertensive kidney damage; CTIN, chronic tubulo-interstitial nephritis; ON, obstructive nephropathy.

Figure 2. Prevalence of subgroups among hospitalized patients with CKD by geographic regions in 2015

Funding

  • Other NIH Support