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Abstract: SA-PO775

Dry Mouth with Hemodialysis Patients Results in Hypogeusia

Session Information

Category: Dialysis

  • 601 Standard Hemodialysis for ESRD


  • Suzuki, Miho, Yabuki hospital, Yamagata, Japan
  • Masakane, Ikuto, Honcho-Yabuki Clinic, Yamagata, Japan

Dry mouth is one of the causes of taste disorder and affects excessive intake of salt or decreased appetite. Dry mouth often occurs in hemodialysis (HD) patients. However, there have been few reports about dry mouth associated with taste disorder in HD patients. In this study, we examined salivation secretion and taste sensitivity in Maintenance HD patients.


Inclusion criteria were 46 HD patients who complained of dry mouth by symptomatic investigation and were recognized to have low taste sensitivity from the taste test results. 17 individuals (mean age; 67.9±9.1 yr, 10 men) agreed to enroll in the study. The subjects were divided by unstimulated whole salivation into Low Salivation (LS; 7 patients) and Normal Salivation (NS; 10 patients) groups. Taste sensitivity was determined by the filter paper disc method. Taste sensitivity of sweet, salt, sour and bitter tastes were evaluated. The sample with each taste has five levels of concentration. Low Taste Sensitivity was determined when patients were not able to recognize level three. Salt intake was determined by a 3-day food diary. These results were compared between the two groups by using a Student t-test or Mann-Whitney's U test.


Of the low taste sensitivity patients 7 were categorized as LS and 9 were categorized as NS. Of the subjects that complained of taste disorder symptoms; 4 in the LS group complained of hypogeusia; and 6 in the NS group complained of hypogeusia, pantogeusia, heterogeusia and hemigeusia. Between the LS and NS groups respectively, the ages were (70.9 ± 7.3 vs 65.8 ± 10.1 yr p = 0.275), and the dialysis vintage was (114.9 ± 96.7 vs 75.8 ± 78.3 mth p = 0.353). The taste sensitivity of the four tastes showed no significant difference. But salt taste sensitivity (5.0 ± 1.8 vs 3.2 ± 1.7 points p = 0.088) tended to be lower in the LS group than the NS group. Salt intake showed no significant difference (6.3 g ± 2.0 vs 8.1 ± 2.1 g p = 0.096).


There are many causes & symptoms of taste disorders. Dry mouth tends to result in hypogeusia, especially in patients with less salt taste sensitivity. However, salt intake showed no significant difference between the LS and NS groups. Therefore, it cannot be determined that dry mouth results in a taste disorder which then results in an excessive intake of salt.