Abstract: SA-PO711

Novel Score to Predict the Risk of Loss of Technique at 3 Months in Patients with Peritonitis Associated with Peritoneal Dialysis

Session Information

  • Peritoneal Dialysis - II
    November 04, 2017 | Location: Hall H, Morial Convention Center
    Abstract Time: 10:00 AM - 10:00 AM

Category: Dialysis

  • 608 Peritoneal Dialysis

Authors

  • Jimenez cornejo, Monica Consuelo, Hospital Civil De Guadalajara, University of Guadalajara, Guadalajara, Mexico
  • Murillo brambila, Daniel, Hospital Civil De Guadalajara, University of Guadalajara, Guadalajara, Mexico
  • Chavez, Jonathan, Hospital Civil De Guadalajara, University of Guadalajara, Guadalajara, Mexico
  • Renoirte, Karina, Hospital Civil De Guadalajara, University of Guadalajara, Guadalajara, Mexico
  • Abundis Mora, Gabriela Jazmín, Hospital Civil De Guadalajara, University of Guadalajara, Guadalajara, Mexico
  • Rubio, Ricardo, Hospital Civil De Guadalajara, University of Guadalajara, Guadalajara, Mexico
  • Amezcua, Hernando, IMSS, Zapopan, Mexico
  • Garcia-Garcia, Guillermo, Hospital Civil De Guadalajara, University of Guadalajara, Guadalajara, Mexico
Background

CKD is a major public health problem in Mexico, the incidence of CKD G5 reach 377 patients pmh, the most frequent modality of RRT is PD. Peritonitis is the most frequent cause of technique failure.

Methods

A descriptive, prospective study of 116 PD patients with peritonitis, we determinate by multivariate analysis the risk factors associated with loss of peritoneal technique at 3 months of onset of peritonitis Data are shown in numbers, percentages, mean, standard deviation, chi square, according the magnitude of the OR we develop a numeric scale, a ROC curve was done to determinate the AUC of the best cut-off point to predict loss of peritoneal technique at 3 months of the onset of peritonitis.

Results

A total of 116 episodes of peritonitis were recorded, fifty-two (45%) of them resulted in technique failure. Factors independently associated with increased risk were: diarrhea (OR =3.0, P = 0.023), >1000 white cells in PD fluid (OR =1.98, P = 0.006), turbid DP fluid (OR = 5.0, P = 0.032), time in PD (OR=3.6 P=0.014) and first episode of peritonitis (OR =4, P = 0.002). Severity score was set as low risk (≤ 5 points) and high risk (≥6 points). The incidence of technique failure in the first 3 months occurs more often in high-risk patients (OR 7.2 IC95% 1.2 to 2.3, P <0.001), the AUROC was 0.686, sensitivity 70% and specificity 32%

Conclusion

In patients with peritonitis associated with PD, a simple score including clinical and laboratory data available on admission may predict the risk of technique failure in the next 3 months; this finding may assist clinician to ensure a close follow-up of the patient at high-risk and anticipate possible outcomes.

Funding

  • Other U.S. Government Support