Abstract: SA-PO765

Cognitive Impairment and Depression among Hispanic Hemodialysis Patients in Puerto Rico

Session Information

Category: Dialysis

  • 601 Standard Hemodialysis for ESRD

Authors

  • Sanchez, Neysha J., University of Puerto Rico, San Juan, Puerto Rico, United States
  • Delgado garrastegui, Angel Fernando, University of Puerto Rico, Medical science campus, San Juan, Puerto Rico, United States
Background

Cognitive Impairment and Depression are prevalent in patients with End Stage Renal Disease on hemodialysis (HD). Studies have shown as many as two thirds of these patients suffer cognitive impairment, which is higher than in the age matched population. Cognitive Impairment in HD patients is an important public health problem given the increasing age and prevalence of comorbidities, such as diabetes and vascular disease. Similarly, depression with prevalence of 40% in these patients has significant effects on individual patient well-being and delivery of medical care. The prevalence of cognitive impairment and depression is unknown in our Hispanic population.

Methods

The population is 43 of 55 patients receiving ambulatory HD at The University Hospital in PR three times per week. Exclusion criteria included patients suffering from dementia or prior cerebrovascular accident. The instrument included The Beck Depression Inventory and The General Practitioner assessment of Cognition. Statistical Analysis was summarized using descriptive statistics for continuous variables and frequency distributions for categorical variables. Chi-square (X 2) test and Fisher's test were conducted to evaluate the associations between cognitive impairment and depression.

Results

The prevalence of depression was 26.30% and of cognitive impairment 88%. There was no statistically significant association between age, gender, education status, income or dialysis vintage and depression. Most of the subjects who screened positively for depression were active smokers (p-value < 0.05). There was no statistically significant association between age, gender, smoking status, education status, income or dialysis vintage and cognitive impairment.

Conclusion

There were no statistical significant associations between gender, age, education, income and dialysis vintage with the presence of cognitive impairment and depression. Subjects who screened positively for depression reported more smoking. As found in others studies, cognitive impairment was common and undiagnosed in HD patients. Further studies are needed to determine whether dialysis exacerbates the cognitive impairment attributable to underlying disease. Contrary to the findings in our study, depression and education levels were shown to be independent predictors for cognitive impairment in multivariate analysis of other studies.