Abstract: FR-PO1117
Quality of Life Among Prevalent Kidney Stone Formers
Session Information
- Health Maintenance, Nutrition, and Metabolism
November 07, 2025 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Health Maintenance, Nutrition, and Metabolism
- 1500 Health Maintenance, Nutrition, and Metabolism
Authors
- Bhattarai, Shreeyukta, Brown University Health, Providence, Rhode Island, United States
- Lu, Jason, Brown University Health, Providence, Rhode Island, United States
- Shringi, Sandipan, Brown University Health, Providence, Rhode Island, United States
- Raker, Christina A., Brown University Health, Providence, Rhode Island, United States
- Tang, Jie, Brown University Health, Providence, Rhode Island, United States
Background
Quality-of-life (QOL) measures have not been well studied among kidney stone formers (KSF). Here, we aim to investigate the determinants and prognostic value of QOL in this unique patient population.
Methods
We examined QOL measurements (SF-12 and Healthy Days Measures) among prevalent KSF and the associated risk of death using the National Health and Nutrition Examination Surveys (NHANES) III, 2007-2018, and their linked mortality file. Depending on the outcome measures, both logistic regression and Cox regression models were used.
Results
43,917 participants were eligible for the final analysis, including 3,514 KSF. KSF tended to be non-Hispanic, white males, and had lower socioeconomic status (SES). KSF had significantly lower QOL measured by SF12 compared to non-KSF in both unadjusted and adjusted logistic regression analyses (Figure 1), and the overall QOL measures did not change over time, p=0.40. According to the Healthy Days questionnaire conducted from 2007 to 2012, both physical health and pain scores were significantly worse, and there was also a trend toward worse mental health among KSF in the regression analysis (Table 1). Lastly, poor QOL measures among KSF is strongly associated with higher all-cause and cardiovascular mortalities (Figure 2).
Conclusion
KSF had worse QOL compared to non-KSF, and QOL significantly predicted survival. Among KSF, both physical health and pain appeared to account for the poor QOL
Healthy Days Measures, NHANES 2007 -2012 subset (n=14,576)
| KSF | No KSF | Unadjusted analysis | Adjusted analysis | ||||
| Days (n) | Weighted % | Unweighted n | Weighted % | Unweighted n | P-value | OR (95% CI), P-value | |
| Poor physical health | Zero 1-15 16-30 | 59.2 30.5 10.3 | 735 410 171 | 66.6 25.7 7.7 | 8,587 3497 1,176 | <0.001 | 1.21 (1.04-1.40) P=0.01 |
| Poor mental health | Zero 1-15 16-30 | 58.9 29.7 11.3 | 788 379 149 | 58.6 33.0 8.4 | 8,021 4,070 1,169 | 0.006 | 1.14 (0.99-1.32) P=0.07 |
| Inactivity due to poor physical/mental health | Zero 1-15 16-30 | 75.7 18.4 5.8 | 979 247 90 | 80.5 15.4 4.1 | 10,705 1,968 587 | 0.002 | 1.19 (0.99-1.44) P=0.06 |
| Pain causing difficulty in usual activity | Zero 1-15 16-30 | 58.0 27.1 14.8 | 763 336 217 | 70.3 21.2 8.5 | 9,308 2,776 1,176 | <0.001 | 1.40 (1.23-1.59) P<0.001 |
Multiple ordinal logistic regression; adjusted of sex, age, race, insurance, education, BMI, HTN, DM, smoking and alcohol.