Abstract: TH-PO0996
Kirpa Kit Procedure for Manual Hemodialysis: A Pilot Case Report Series in Resource-Limited Settings
Session Information
- Diversity and Equity in Kidney Health
November 06, 2025 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Diversity and Equity in Kidney Health
- 900 Diversity and Equity in Kidney Health
Authors
- Borbolla-Flores, Paola, Hospital Universitario Dr Jose Eleuterio Gonzalez, Monterrey, N.L., Mexico
- Gomez Villarreal, Juan Pablo, Hospital Universitario Dr Jose Eleuterio Gonzalez, Monterrey, N.L., Mexico
- Garza Treviño, Ricardo Abraham, Christus Muguerza Sistemas Hospitalarios SA de CV, Monterrey, N.L., Mexico
- Olivo Gutierrez, Mara Cecilia, Hospital Universitario Dr Jose Eleuterio Gonzalez, Monterrey, N.L., Mexico
- Rizo Topete, Lilia Maria, Hospital Universitario Dr Jose Eleuterio Gonzalez, Monterrey, N.L., Mexico
Background
Renal replacement therapy (RRT) can be lifesaving, yet access is often disrupted in low-resource settings. Traditional RRT methods depend on electricity, clean water, specialized equipment, and trained personnel—resources unavailable in critical situations. To address this gap, a simplified manual hemodialysis procedure with Kirpa Kit was developed.
Methods
This pilot case series evaluated the Kirpa Kit’s procedure feasibility in 3 critically ill patients with severe AKI and no access to conventional dialysis. The system, costing ~$70 USD, uses a simple extracorporeal circuit with a filter, stopcocks, syringes, and tubing. It requires only one central venous catheter and functions without electricity or dialysis machines. Blood is manually cycled through the filter to achieve solute clearance and ultrafiltration. Dialysis is performed using a bicarbonate-glucose solution. Notably, none of the three patients experienced hemodynamic instability during or immediately after the intervention, and no anticoagulation was used in the circuit.
Results
Patient 1: A 37-y/o trauma patient with septic shock and worsening AKI was dialyzed using the Kirpa Kit after ICU CRRT was unavailable.
Patient 2: A 72-y/o man with diabetic CKD and sepsis developed anuria and was treated with 600 mL of ultrafiltration in one hour.
Patient 3: A 59-y/o with cirrhosis and surgical complications had improved hemodynamics and metabolic status after Kirpa Kit dialysis, including 800 mL ultrafiltration and a 5.23% reduction in urea.
Conclusion
The Kirpa Kit demonstrated clinical effectiveness and safety as a temporary dialysis method in extreme conditions. Its portability, low cost, and simplicity allow broader access to RRT in underserved areas. This approach could bridge patients to standard therapies or provide life-saving support during crises when conventional dialysis is not an option.